Results 41 to 50 of about 553,337 (279)
, 2006 The rapid pace of growth in China's total energy consumption over the past decade and the seemingly unrestrained rise of oil prices have generated a critical mass of discussion about China's energy security.
Zha Daojiong
core
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Russian gas and european energy security: Interdependence following the crisis with Georgia and the Ukraine [PDF]
Revista CIDOB d'Afers Internacionals, 2009 At the present time, gas represents one of the main energy raw materials that are used for producing electricity and other private uses. The dual political conflict between the Ukraine and the Russian Federation (winter 2005 and Christmas 2008 and 2009 ...
Domenico Gullo, Jorge Tuñón
doaj
EMPIRIA: Revista de Metodología de Ciencias Sociales, 2023 Este artículo analiza iniciativas de solidaridad dirigidas a grupos vulnerabilizados en España en el contexto de la crisis posterior a 2008. El análisis se basa en la perspectiva de Polanyi sobre los contramovimientos que se desarrollan en la sociedad ...
Maria Antònia Carbonero Gamundí +1 more
doaj +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Informatics, 2021 Rational models of human behavior aim to predict, possibly control, humans. There are two primary models, the cognitive model that treats behavior as implicit, and the behavioral model that treats beliefs as implicit.
William F. Lawless
doaj +1 more source
Monetary Policies in Interdependent Economies: An Open Economy Explanation for Base Drift and Price-Level Non-Trend-Stationarities [PDF]
, 1995 Most nations have experienced \u27base drift\u27 of their money stocks and associated price-level non-trend-stationarities. Recent explanations for this fact have emphasized tensions among various possible objectives of central banks in closed-economy or
Daniels, Joseph, VanHoose, David D.
core +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source