Results 101 to 110 of about 11,245,830 (292)

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Gallium‐Assisted Platinum Isolation: Formation of Multiple Pt Species in Ga‐Pt Liquid Metal Catalysts

open access: yesSmall Structures
Ga‐Pt liquid metal catalysts have emerged as promising catalysts, offering improved catalytic performance compared to pure platinum for reactions such as propane dehydrogenation.
Tzung‐En Hsieh   +8 more
doaj   +1 more source

Dynamic Visual Warning Cues and Monochrome Gradient Types: Key Factors Shaping AR-HUD Warning Interface Design for Drivers

open access: yesIEEE Access
With the widespread application of Augmented Reality Head-Up Displays (AR-HUDs) in automotive systems, optimizing their visual warning interface design is critical for enhancing driving safety and user experience.
Weimin Zhai, Qing Zhu, Pingting Hao
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Interface Design an Hochschulen

open access: yesi-com, 2002
Wolfgang Henseler, Frank Zebner
openaire   +3 more sources

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Modelo e diretrizes para o processo de design de interface WEB adaptativa [PDF]

open access: yes, 2008
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-graduação em Engenharia e Gestão do ConhecimentoEsta tese propõe um modelo e diretrizes para o Processo de Design de Interface Web Adaptativa (PDIWA), visando ...
Batista, Claudia Regina
core  

Físchlár on a PDA: handheld user interface design to a video indexing, browsing and playback system [PDF]

open access: yes, 2001
The Físchlár digital video system is a web-based system for recording, analysis, browsing and playback of TV programmes which currently has about 350 users.
Murphy, Noel   +5 more
core   +2 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

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