Results 91 to 100 of about 11,245,830 (292)

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

Adaptive Interface for Complex Software:A Case Study on Macromedia Dreamweaver

open access: yes, 2009
[[abstract]]Professional software has become increasingly complex as advances in technology permit substantially more functionality to be provided to the user so that there are a large number of unused features.
Ya-Jen Cheng
core  

Trends in Adaptive Interface Design for Smart Wheelchairs

open access: yes, 2008
This chapter introduces the main trends in the design of interfaces for smart wheelchairs. It stresses the importance of taking into account their similarity with autonomous mobile robots and the restrictions posed by the special characteristics of the ...
Cagigas, Daniel   +9 more
core   +1 more source

Tacit Learning in an Extended Interior Design Studio [PDF]

open access: yes, 2019
5th DRS Learn X Design International Conference for Design Education Researchers: Insider Knowledge, 9-12 July 2019, METU, Ankara202403 bckwVersion of RecordSelf ...
Venkatesh, A   +5 more
core   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Supporting Sensemaking of Complex Objects with Visualizations: Visibility and Complementarity of Interactions

open access: yesInformatics, 2016
Making sense of complex objects is difficult, and typically requires the use of external representations to support cognitive demands while reasoning about the objects.
Kamran Sedig   +3 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

The design of a mobile user interface for an interest rate calculator [PDF]

open access: yes, 2012
Includes abstract.Includes bibliographical references.In our search towards an interactive mobile fixed rate calculator, in this dissertation, we are interested in the human-centred design and in particularly exploring the mobile user interface design ...
Swanepoel, Arie Willem
core   +1 more source

Evaluasi  Dan Redesain Antarmuka Website megapolitanpos.com Menggunakan Metode Usability Testing Dan Heuristic Evaluation

open access: yesComputer Science
Megapolitanpos.com, a Press Council-verified online news portal, faces usability problems such as complex navigation, unorganized layout, and less attractive visual design. This research aims to identify problems, redesign the interface, and improve user
Jonathan Tanuwijaya, Arfhan Prasetyo
doaj   +1 more source

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