Results 71 to 80 of about 525,544 (263)
‘Is this a vision? is this a dream?’: Finding New Dimensions in Shakespeare’s Texts
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Michael Best
doaj +1 more source
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
DEPLOYMENT OF A DEEP LEARNING MODEL TO ASSIST PATHOLOGISTS WITH DONOR KIDNEY BIOPSY EVALUATION
Joseph Gaut +5 more
doaj +1 more source
The Renaissance English Knowledgebase (REKn) is an electronic knowledgebase consisting of primary and secondary materials (text, image, and audio) related to the Renaissance period.
Raymond Siemens
doaj +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Video Oyunlarındaki Arayüz Tasarımının Oyun Afişi Üzerindeki Yansımaları
Bu çalışmada popüler ve başarılı video oyunlarının arayüz ve afiş tasarımları arasındaki bağın ortaya çıkarılması amaçlanmıştır. Arayüzler oyunun oynanabilmesi ve oyuncu ile bağ kurmayı sağladığı için çok önemlidir.
Hüdaver Altıntuğlu
doaj
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Making sense of complex objects is difficult, and typically requires the use of external representations to support cognitive demands while reasoning about the objects.
Kamran Sedig +3 more
doaj +1 more source
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source

