Results 61 to 70 of about 11,245,830 (292)
Transforming desalination brine into highly reactive magnesium oxide and life cycle analysis
The sustainable production of magnesium oxide (MgO) from reject brine at a desalination facility in Singapore presents a promising alternative to traditional building materials. This study investigates the properties and extraction methods of MgO derived
Hasanthi L. Senevirathna +4 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Enhancing CO2 Adsorption on MgO: Insights into Dopant Selection and Mechanistic Pathways
Inspired by our recent success in designing CO2-phobic and CO2-philic domains on nano-MgO for effective CO2 adsorption, our ongoing efforts focus on incorporating dopants into pristine MgO to further enhance its CO2 adsorption capabilities.
Shunnian Wu +4 more
doaj +1 more source
Design assistance for user interface designers [PDF]
The paper addresses a research approach in the area of user interface development tools, namely to discover the helpful, structured, and organised ways to integrate the use of guidelines, standards, and styles into the development tools. The aim of this research approach is to assist the user interface designer during the design process with the help ...
openaire +2 more sources
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
C9H15F6N2O2P, triclinic, P1̄ (no. 2), a = 8.678(8) Å, b = 9.085(9) Å, c = 10.279(8) Å, α = 84.23(2)∘, β = 79.02(2)∘, γ = 62.103(14)∘, V = 62.10(1) Å3, Z = 2, Rgt (F) = 0.0730, wRref (F 2) = 0.1663, T = 296 K.
Mao Zhiwei +3 more
doaj +1 more source
Designing improvisational interfaces [PDF]
This paper examines the possibilities for creative interaction with computers, in particular modes of interaction based on improvisation and spontaneous creative discovery.We consider research findings from studies in psychology that investigate how humans improvise together to see what could be useful in helping us to design systems that provide new ...
Jon McCormack, Mark d'Inverno
openaire +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source

