Results 41 to 50 of about 11,245,830 (292)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Market user interface design [PDF]

Proceedings of the 13th ACM Conference on Electronic Commerce, 2012
Despite the pervasiveness of markets in our lives, little is known about the role of user interfaces (UIs) in promoting good decisions in market domains. How does the way we display market information to end users, and the set of choices we offer, influence users' decisions?
Seuken, Sven, Parkes, David C, Horvitz, Eric, Jain, Kamal, Czerwinski, Mary, Tan, Desney   +5 more
openaire   +3 more sources

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

The Energy Level Alignment at the Buffer/Cu(In,Ga)Se2 Thin‐Film Solar Cell Interface for CdS and GaOx

Advanced Materials Interfaces
Sputter‐deposited GaOx (i.e., oxygen‐deficient gallium oxide) films are evaluated as a potential replacement for the standard CdS buffer layers in Cu(In,Ga)Se2 (CIGSe) based thin‐film photovoltaics.
Donald Valenta, Hasan Arif Yetkin, Tim Kodalle, Jakob Bombsch, Raul Garcia‐Diez, Claudia Hartmann, Shigenori Ueda, Roberto Félix, Johannes Frisch, Lucas Bodenstein‐Dresler, Regan G. Wilks, Christian A. Kaufmann, Marcus Bär   +12 more
doaj   +1 more source

Development of Instrument Transmitter Protecting Device against High-Temperature Condition during Severe Accidents

Science and Technology of Nuclear Installations, 2014
Reliable information through instrumentation systems is essential in mitigating severe accidents such as the one that occurred at the Fukushima Daiichi nuclear power plant. There are five elements which might pose a potential threat to the reliability of
Min Yoo, Sung Min Shin, Hyun Gook Kang
doaj   +1 more source

Research on the Influence of User and Graphic–Text Combined Icon Construal Level Fitting on Visual Cognition

Applied Sciences, 2022
Based on the individual traits of the user’s construal level differences, this study examines the visual cognition differences of graphic–text combined icon concreteness in the interface between users with high and low construal levels.
Yanfei Zhu, Ying Li, Yun Lin, Mo Chen, Qi Guo, Zhisheng Zhang   +5 more
doaj   +1 more source

Design of haptic interfaces for therapy [PDF]

Proceedings of the SIGCHI Conference on Human Factors in Computing Systems, 2009
Touch is fundamental to our emotional well-being. Medical science is starting to understand and develop touch-based therapies for autism spectrum, mood, anxiety and borderline disorders. Based on the most promising touch therapy protocols, we are presenting the first devices that simulate touch through haptic devices to bring relief and assist clinical
Vaucelle, Catherine Nicole, Bonanni, Leonardo Amerigo, Ishii, Hiroshi   +2 more
openaire   +4 more sources

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

The OÆSE endstation at BESSY II: operando X-ray absorption spectroscopy for energy materials

Journal of Synchrotron Radiation
The investigation of a wide range of energy materials under relevant operation conditions, allowing for real-time investigations of the (electro)chemical mechanisms governing the performance of related applications, is enabled by the new Operando ...
Raul Garcia-Diez, Johannes Frisch, Marianne van der Merwe, Romualdus Enggar Wibowo, Mihaela Gorgoi, Elmar Kataev, Catalina E. Jimenez, Mauricio D. Arce, William Smith, Wilson Quevedo-Garzon, Regan G. Wilks, Dirk Wallacher, Leonhard J. Reinschlüssel, Gülen C. Tok, Hubert A. Gasteiger, Marcus Bär   +15 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source