Results 51 to 60 of about 525,544 (263)

Design assistance for user interface designers [PDF]

open access: yesProceedings of IEEE International Conference on Systems, Man and Cybernetics, 2002
The paper addresses a research approach in the area of user interface development tools, namely to discover the helpful, structured, and organised ways to integrate the use of guidelines, standards, and styles into the development tools. The aim of this research approach is to assist the user interface designer during the design process with the help ...
openaire   +2 more sources

Combinatorial ab initio calculations and core spectroscopy unravel the electronic structure of nickel cobalt manganese oxide

open access: yesScientific Reports
The rising interest in complex oxides for energy storage applications calls for the development of efficient computational schemes that enable exploring the vast configurational space of these materials to guide and complement experiments.
Timo Reents   +6 more
doaj   +1 more source

Transforming desalination brine into highly reactive magnesium oxide and life cycle analysis

open access: yesWatershed Ecology and the Environment
The sustainable production of magnesium oxide (MgO) from reject brine at a desalination facility in Singapore presents a promising alternative to traditional building materials. This study investigates the properties and extraction methods of MgO derived
Hasanthi L. Senevirathna   +4 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Designing improvisational interfaces [PDF]

open access: yes, 2016
This paper examines the possibilities for creative interaction with computers, in particular modes of interaction based on improvisation and spontaneous creative discovery.We consider research findings from studies in psychology that investigate how humans improvise together to see what could be useful in helping us to design systems that provide new ...
Jon McCormack, Mark d'Inverno
openaire   +1 more source

Enhancing CO2 Adsorption on MgO: Insights into Dopant Selection and Mechanistic Pathways

open access: yesBiomimetics
Inspired by our recent success in designing CO2-phobic and CO2-philic domains on nano-MgO for effective CO2 adsorption, our ongoing efforts focus on incorporating dopants into pristine MgO to further enhance its CO2 adsorption capabilities.
Shunnian Wu   +4 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

The crystal structure of 1-(4-carboxybutyl)-3-methyl-1H-imidazol-3-ium hexafluoridophosphate, C9H15F6N2O2P

open access: yesZeitschrift für Kristallographie - New Crystal Structures
C9H15F6N2O2P, triclinic, P1̄ (no. 2), a = 8.678(8) Å, b = 9.085(9) Å, c = 10.279(8) Å, α = 84.23(2)∘, β = 79.02(2)∘, γ = 62.103(14)∘, V = 62.10(1) Å3, Z = 2, Rgt (F) = 0.0730, wRref (F 2) = 0.1663, T = 296 K.
Mao Zhiwei   +3 more
doaj   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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