Results 111 to 120 of about 11,245,830 (292)

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Abordagem semiótica de design de interface para ambientes de aprendizagem com suporte ao pensamento crítico: um estudo de caso [PDF]

, 2005
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Ciência da ComputaçãoExistem desenvolvedores de software que acreditam que uma interface é apenas para apresentar de maneira mais amigável ...
Oliveira, Augusto César Melo de
core  

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Redundancy in interface design and its impact on intuitive use of a product in older users [PDF]

, 2009
Many older adults have difficulty using modern consumer products due to their complexity both in terms of functionality and interface design. It has been observed that older people also have more problems learning new systems.
Mahar, Doug P, Gudur, Raghavendra R., Gudur, Raghavendra; id_orcid, Blackler, Alethea L., Popovic, V, Mahar, Douglas P., Popovic, Vesna, Blackler, Alethea, Blackler, A, Mahar, Doug, Gudur, Raghavendra R   +10 more
core  

Optimization Analysis of Emergency Unlocking Control Scheme for Metro Vehicles

机车电传动, 2019
Based on the design of vehicle and signal system interface, the train operation control strategy and door state setting after the emergency unlocking of subway vehicle was analyzed and discussed. By optimizing the existing control circuit of the vehicle,
Wenwen ZHANG, Qian ZHANG
doaj  

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Interface Currents : evaluating a fluid interface for tabletop collaboration [PDF]

, 2015
Masters ThesisLarge screen vertical and horizontal displays provide new opportunities to support individual and collaborative activities especially in terms of creativity and design tasks.
Hinrichs, Uta
core   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Avaliação da interface de um aplicativo computacional através de teste de usabilidade, questionário ergonômico e análise gráfica do design [PDF]

, 2003
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia de Produção.O presente trabalho apresenta os conceitos envolvidos com a interface, aspectos ligados ao perfil do usuário e ...
Barros, Vanessa Tavares de Oliveira
core  

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source