Results 111 to 120 of about 15,991,228 (373)

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

Supporting Sensemaking of Complex Objects with Visualizations: Visibility and Complementarity of Interactions

open access: yesInformatics, 2016
Making sense of complex objects is difficult, and typically requires the use of external representations to support cognitive demands while reasoning about the objects.
Kamran Sedig   +3 more
doaj   +1 more source

Ecological interface design for eco-driving [PDF]

open access: yes
Eco-driving issues are of high priority at the moment. Research suggests that a change in driving style can reduce fuel consumption and emissions by around 15% in many cases. In response to this need, the UK Foot-LITE project developed an in-car feedback
Birrell, Stewart A., Young, Mark S.
core  

Adaptation is a Game [PDF]

open access: yes, 2013
Control data variants of game models such as Interface Automata are suitable for the design and analysis of self-adaptive ...
Bruni, Roberto   +4 more
core  

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

The use of analytical models in human-computer interface design [PDF]

open access: yes
Some of the many analytical models in human-computer interface design that are currently being developed are described. The usefulness of analytical models for human-computer interface design is evaluated.
Gugerty, Leo
core   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Evaluasi  Dan Redesain Antarmuka Website megapolitanpos.com Menggunakan Metode Usability Testing Dan Heuristic Evaluation

open access: yesComputer Science
Megapolitanpos.com, a Press Council-verified online news portal, faces usability problems such as complex navigation, unorganized layout, and less attractive visual design. This research aims to identify problems, redesign the interface, and improve user
Jonathan Tanuwijaya, Arfhan Prasetyo
doaj   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

open access: yesFEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc   +8 more
wiley   +1 more source

Tuning the morphology and energy levels in organic solar cells with metal–organic framework nanosheets

open access: yesScientific Reports
Metal–organic framework nanosheets (MONs) have proved themselves to be useful additives for enhancing the performance of a variety of thin film solar cell devices. However, to date only isolated examples have been reported. In this work we take advantage
Kezia Sasitharan   +7 more
doaj   +1 more source

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