Results 31 to 40 of about 236,428 (250)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
The L2 Acquisition of French Interrogatives: Pragmatic Inferences in Clefted wh-Questions
Languages, 2021 The present study aims to elaborate on the understanding of the second language (L2) acquisition of French interrogatives by focusing on clefted (subject) wh-questions, structures that are largely absent in prior L2 literature.
Emilie Destruel, Bryan Donaldson
doaj +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
The subject realization in L2 Spanish by German L1 speakers
IsoglossThis article deals with the realization of referential subjects in the L2 Spanish of German (adult) native speakers. The acquisition of a null subject grammar by speakers of a non-null subject language has drawn considerable attention in generative ...
Anna Kocher
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Parametrical Study of Freshwater–Saltwater Interface Dynamic
Modelling and Simulation in Engineering, 2023 In this paper, a saltwater intrusion model, in view to study the dynamics of the interface between the saltwater and the freshwater in a coastal aquifer, is established. This dynamic is caused by an injection of saltwater and a freshwater pumping through
Mody Lo, Daouda Sangare
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Interface vulnerability in bilingual grammars?
IsoglossBilingual children typically produce more redundant pronominal subjects than monolingual children in null subject languages like Spanish in contact with non-null subject languages like English (Montrul & Sánchez-Walker, 2013; Montrul, 2004; Paradis ...
Eider Etxebarria, Silvina Montrul
doaj +1 more source
Mussel adhesive protein coating: A potential therapeutic method for self-healing of cracked teeth
Dental Hypotheses, 2015 Introduction: Nowadays, cracked tooth syndrome is the third main cause of tooth extraction, following caries and periodontal diseases, done in almost all the dental clinics. Nevertheless, the diagnosis and treatment of this condition remain controversial.
Li Bo-Lin, Cao Ying, Li Quan-Li
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Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source