Results 61 to 70 of about 256,853 (313)

Analytical solution for one-dimensional consolidation of double-layered soil with exponentially time-growing drainage boundary

open access: yesInternational Journal of Distributed Sensor Networks, 2018
In this article, the exponentially time-growing drainage boundary is introduced to study the one-dimensional consolidation problem of double-layered soil.
Wenbing Wu   +4 more
doaj   +1 more source

SBMLSimulator: A Java Tool for Model Simulation and Parameter Estimation in Systems Biology

open access: yesComputation, 2014
The identification of suitable model parameters for biochemical reactions has been recognized as a quite difficult endeavor. Parameter values from literature or experiments can often not directly be combined in complex reaction systems.
Alexander Dörr   +3 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

A Rigorous Sharp Interface Limit of a Diffuse Interface Model Related to Tumor Growth

open access: yes, 2016
In this paper, we study the rigorous sharp interface limit of a diffuse interface model related to the dynamics of tumor growth, when a parameter ε, representing the interface thickness between the tumorous and non-tumorous cells, tends to zero.
ROCCA E   +5 more
core   +1 more source

Research of Authentication Method of Intrinsically Safe Interconnection of Coal Mine Monitoring and Control System

open access: yesGong-kuang zidonghua, 2010
According to characteristics of complex structure and various interconnection equipments with increasing quantity of coal mine monitoring and control system,the paper analyzed applicability of traditional authentication method of intrinsically safe ...
ZOU Zhe-qiang
doaj  

A Molecular Dynamics Study on the Effects of Nanostructural Clearances on Thermal Resistance at a Lennard-Jones Liquid-Solid Interface

open access: yesJournal of Thermal Science and Technology, 2011
The effects of the surface structures and the surface structural clearances at the nanometer scale on the thermal resistance at a Lennard-Jones liquid-solid interface, as well as the self-diffusion behaviors of liquid molecules, were investigated ...
Masahiko SHIBAHARA, Kiyoshi TAKEUCHI
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

An analysis of convection in a mushy layer with a deformable permeable interface [PDF]

open access: yes, 2008
We study the dynamics of a mushy layer in directional solidification for the case of a thin near-eutectic mush with a deformable and permeable mush–liquid interface.
Roper, S.M., Voorhees, P.W., Davis, S.H.
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

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