Results 51 to 60 of about 256,853 (313)

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

OpenGPI Release 0.2: An Open and Generic Parameter Interface

, 2010
OpenGPI (Open Generic Parameter Interface) is an open-source software aiming at providing a configuration interface in a very generic way. The required configuration options of another software are described by metadata (XML) through which OpenGPI ...
Krause, M.J., Zeltmann, U. (8372145), Fietz, J. (8372142), Fietz, J., Zeltmann, U., Wlozka, M. (8372148), Bockelmann, H. (8372154), Krause, M.J. (8372139), Wlozka, M., Baumann, M., Baumann, M. (8372151), Bockelmann, H.   +11 more
core   +1 more source

Shear characteristics of anchoring solid-soil interface in filled soil

Yantu gongcheng xuebao, 2018
A testing apparatus simulating the frictional behavior of anchoring solid-soil interface is developed to study the real response of the anchoring solid-soil interface for anchor system.
YANG Qing-guang , LIANG Ling-chuan , YANG Yi-fei , DENG Fang-geng
doaj   +1 more source

Numerical Analysis of Flexible Pavements Using Micromechanical Approach [PDF]

مجله مدل سازی در مهندسی, 2015
In finite element analysis of flexible pavement, general characteristics’ layers usually are used. This issue does not specify effects of micromechanical behavior and its impact on the overall behavior of pavement.
Gholamali Shafabakhsh, Ahmad Mehrabi
doaj   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Mechanical properties of mandibular and maxillary bone collagen fibrils based on nonlocal elasticity theory

Biophysical Reports
In this paper, the mechanical properties of collagen fibrils in the cortical bone and cortical-trabecular bone interface of the human mandible and maxilla have been investigated.
Elaheh Alibeigi Beni, Alireza Shahidi, Behnaz Ebadian   +2 more
doaj   +1 more source

Numerical solution and parameter estimation of multi-interface heat conduction models

四川大学学报. 自然科学版, 2022
This paper mainly studies the numerical solution and parameter estimation of a multi-interface heat conduction equation. Firstly, the heat conduction equation and interface conditions are discretized to tridiagonal linear equations by using the finite ...
CHEN Xiang-Bing, MIN Xin-Chang, CHEN Chen   +2 more
doaj  

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Parameter Redundancy with Applications in Statistical Ecology [PDF]

, 2014
This thesis is concerned with parameter redundancy in statistical ecology models. If it is not possible to estimate all the parameters, a model is termed parameter redundant.
Hubbard, Ben Arthur
core  

Interface parameters of recycled aggregate concrete considering the distribution of old mortar content

Case Studies in Construction Materials
The amount of Interface Transition Zones (ITZs) in Recycled Aggregate Concrete (RAC) is affected by the mass content of old mortar of Recycled concrete Aggregate (RA).
Gongyu Xia, Yuxi Zhao
doaj   +1 more source