Results 41 to 50 of about 2,961,432 (259)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Reply to determining structural identifiability of parameter learning machines [PDF]

open access: yes, 2016
The paper Ran and Hu (2014, Neurocomputing) examines identifiability and parameter redundancy in classes of models used in machine learning. This note discusses the results on global identifiability and also clarifies that the paper's results on ...
Cole, Diana J.
core   +1 more source

Dynamical law of the phase interface motion in the presence of crystals nucleation

open access: yesScientific Reports, 2022
In this paper, we develop a theory of solid/liquid phase interface motion into an undercooled melt in the presence of nucleation and growth of crystals. A set of integrodifferential kinetic, heat and mass transfer equations is analytically solved in the ...
Liubov V. Toropova, Dmitri V. Alexandrov
doaj   +1 more source

One-Dimensional Nonlinear Consolidation for Soft Clays with Continuous Drainage Boundary Considering Non-Darcy Flow

open access: yesApplied Sciences, 2023
Adopting the non-Darcy flow presented by Hansbo and considering the nonlinear compression and permeability characteristics of soils, the one-dimensional nonlinear consolidation problem of soft clays is investigated by means of a continuous drainage ...
Jin Wu   +4 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Mechanical properties of mandibular and maxillary bone collagen fibrils based on nonlocal elasticity theory

open access: yesBiophysical Reports
In this paper, the mechanical properties of collagen fibrils in the cortical bone and cortical-trabecular bone interface of the human mandible and maxilla have been investigated.
Elaheh Alibeigi Beni   +2 more
doaj   +1 more source

Numerical solution and parameter estimation of multi-interface heat conduction models

open access: yes四川大学学报. 自然科学版, 2022
This paper mainly studies the numerical solution and parameter estimation of a multi-interface heat conduction equation. Firstly, the heat conduction equation and interface conditions are discretized to tridiagonal linear equations by using the finite ...
CHEN Xiang-Bing   +2 more
doaj  

Shear characteristics of anchoring solid-soil interface in filled soil

open access: yesYantu gongcheng xuebao, 2018
A testing apparatus simulating the frictional behavior of anchoring solid-soil interface is developed to study the real response of the anchoring solid-soil interface for anchor system.
YANG Qing-guang , LIANG Ling-chuan , YANG Yi-fei , DENG Fang-geng
doaj   +1 more source

Structural parameter identification of a bolted connection embedded with a piezoelectric interface

open access: yesVietnam Journal of Mechanics, 2020
As the impedance-based technique has been commonly accepted as an innovative structural health monitoring tool, structural identification of a piezoelectric-driven system is of significant interest for damage identification and quantification.
Thanh-Canh Huynh
doaj   +1 more source

(In)compressibility and parameter identification in phase field models for capillary flows [PDF]

open access: yesTheoretical and Applied Mechanics, 2017
Phase field (diffuse interface) models accommodate diffusive triple line motion with variable contact angle, thus allowing for the no-slip boundary condition without the stress singularities.
Dehsara M.   +4 more
doaj   +1 more source

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