Results 121 to 130 of about 665,037 (318)

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Fractionation of Oligosaccharide Nucleoside Mixtures by Single Pass Nano‐Diafiltration

Engineering in Life Sciences
Glycans, a diverse group of complex oligosaccharides, are critical to human physiology and hold significant potential in medical applications and as food additives.
Ulrich Thiele, Tobias Kaloghlian, Jonas Wohlgemuth, Gerald Brenner‐Weiß, André Tschöpe, Matthias Franzreb, Katharina Bleher   +6 more
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Adapting Information Through Tangible Augmented Reality Interfaces

, 2004
Tangible augmented reality interfaces offer a hands on approach for examining objects and exploring the associated information. We describe two tangible augmented reality interfaces that can expose the adaptation of information presented to users about ...
Sinclair, Patrick, Martinez, Kirk
core  

Contextualizing the blogosphere: A comparison of traditional and novel user interfaces for the web

, 2007
In this paper, we investigate how contextual user interfaces affect blog reading experience. Based on a review of previous research, we argue why and how contextualization may result in (H1) enhanced blog reading experiences. In an eyetracking experiment,
Sasse, MA, Laqua, S, Nnamdi Ogbechie, Sven Laqua, M. Angela Sasse, Ogbechie, N   +5 more
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Diretrizes para construção de interfaces gráficas com base na psicologia arquetípica [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Comunicação e Expressão. Programa de Pós-Graduação em Design e Expressão GráficaA presente dissertação intitulada "Diretrizes para construção de interfaces gráficas com base na ...
Schulenburg, Haro Ristow Wippel
core  

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

London Dispersive and Polar Surface Properties of Styrene–Divinylbenzene Copolymer Modified by 5-Hydroxy-6-Methyluracil Using Inverse Gas Chromatography

Crystals
The London dispersive and polar surface properties of solid materials are very important in many chemical processes, such as adsorption, coatings, catalysis, colloids, and mechanical engineering.
Tayssir Hamieh, Vladimir Yu Gus’kov
doaj   +1 more source