Results 101 to 110 of about 665,037 (318)

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Origin and structure of polar domains in doped molecular crystals

open access: yesNature Communications, 2016
Doping can introduce structural distortions in a molecular crystal in the form of polar domains. Here, the authors combine pyroelectric measurements and computation to reveal the molecular structure of such domains in centrosymmetric α-glycine crystals ...
E. Meirzadeh   +7 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Revealing Ionic Transfer Kinetics in Poly(3,4‐Ethylenedioxythiophene)/Multi‐Wall Carbon Nanotubes

open access: yesNano Select
Binder‐free electrodes are critical for advancing supercapacitor performance. Here, we explore the development of multi‐wall carbon nanotubes (MWCNTs) electrodes for supercapacitors by replacing conventional non‐conductive polymer binders, such as poly ...
Juan Su   +6 more
doaj   +1 more source

Tangible interfaces for download: initial observations from users' everyday environments

open access: yes, 2010
Tangible user interfaces (TUIs) have been promoted and discussed in the HCI community for 15 years. Most reported TUIs are research prototypes, available in laboratories or museums. This paper reports an attempt to understand the impact of TUIs in users'
Shelley, Simon   +4 more
core  

How to Talk of Music Technology: An Interview Analysis Study of Live Interfaces for Music Performance among Expert Women

open access: yes, 2020
With the aim of making women’s work in music technology more visible, the organization Women Nordic Music Technology (WoNoMute) has originated conversations with expert women in the form of seminar talks and interviews that are archived digitally.
Jawad, K   +2 more
core  

Desensitization at the Interface [PDF]

open access: yesACS Chemical Biology, 2006
Normal brain function requires the faithful transmission and integration of information on a timescale of milliseconds, and this rapid signaling is mediated by cell membrane receptors that are ligand-gated ion channels. Fast excitatory transmission occurs when synaptically released glutamate opens channels in neighboring neurons, but these channels ...
openaire   +2 more sources

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

A identificação dos objetos de interfaces homem-computador e de seus atributos ergonomicos [PDF]

open access: yes, 1994
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro TecnologicoEsta monografia apresenta um modelo de objetos de interação abstratos ergonômicos - OIAe -, componentes lógicos de uma arquitetura para a geração automática de interfaces homem ...
Cybis, Walter de Abreu
core  

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