Results 111 to 120 of about 665,037 (318)
Creativity at the Interface [PDF]
Science, 2012 The biochemistry that makes life possible is based on a complex network of many thousands of interactions between molecules, and it presents an enormous challenge to the scientists trying to understand it. This special issue of Science , with its focus on computational biology, demonstrates how mathematics and ...
openaire +2 more sources
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
The Acquisition of Recursion: How Formalism Articulates the Child’s Path
Biolinguistics, 2011 We distinguish three kinds of recursion: Direct Recursion (which delivers a ‘conjunction’ reading), Indirect Recursion, and Generalized Transformations. The essential argument is that Direct Recursion captures the first stage of each recursive structure.
Tom W. Roeper
doaj +1 more source
CHILDREN AIMED INTERFACES FOR ANDROID RUNNING DEVICES [PDF]
The paper focuses on the development of mobile interfaces for children. The Android operating system is presented from appearance with its features, hardware support and its advantages over others operating systems.
Tîrziu Georgiana Cristina
core
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
Towards Portable Natural Language Interfaces to Knowledge Bases - The Case of the ORAKEL System -
, 2008 Cimiano P, Haase P, Heizmann J, Mantel M, Studer R. Towards Portable Natural Language Interfaces to Knowledge Bases - The Case of the ORAKEL System -. Data & Knowledge Engineering (DKE).
Haase, Peter +4 more
core +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
TOPOLOGICAL LOCALISATION OF DEFECTS AT ATOMIC SCALE
Image Analysis and Stereology, 2011 The problem addressed in this paper is the detection of defects on atomic structures. The procedure proposed is in two steps. At first a tessellation is built starting from the atoms.
Jean-Paul Jernot +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source