Results 51 to 60 of about 3,810,567 (377)

An interface to an interface to an interface

open access: yes, 2020
The paper relates some experiences from a recent production of orchestrating Conlon Nancarrow Piano Studies for performance on Pipe Organ. Reflections that surfaced during this work concerned the layered nature of interfaces, automation (and thus allusions to the different conceptions of artificial intelligence), and leaky abstractons.
openaire   +2 more sources

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

open access: yesFEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali   +3 more
wiley   +1 more source

Augmenting aesthetic chills using a wearable prosthesis improves their downstream effects on reward and social cognition

open access: yesScientific Reports, 2020
Previous studies on aesthetic chills (i.e., psychogenic shivers) demonstrate their positive effects on stress, pleasure, and social cognition. We tested whether we could artificially enhance this emotion and its downstream effects by intervening on its ...
A. J. H. Haar   +3 more
doaj   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Controls and Interfaces [PDF]

open access: yes, 2016
Reliable powering of accelerator magnets requires reliable power converters and controls, able to meet the powering specifications in the long term. In this paper, some of the issues that will challenge a power converter controls engineer are discussed ...
King, Q.
core   +3 more sources

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Causal Interfaces [PDF]

open access: yes, 2014
The interaction of two binary variables, assumed to be empirical observations, has three degrees of freedom when expressed as a matrix of frequencies. Usually, the size of causal influence of one variable on the other is calculated as a single value, as ...
Eubanks, David A.
core  

Evaluating advanced search interfaces using established information-seeking model

open access: yes, 2009
When users have poorly defined or complex goals search interfaces offering only keyword searching facilities provide inadequate support to help them reach their information-seeking objectives.
schraefel, m.c.   +2 more
core   +1 more source

Cleaning interfaces in layered materials heterostructures [PDF]

open access: yesNature Communications, 2018
Heterostructures formed by stacking layered materials require atomically clean interfaces. However, contaminants are usually trapped between the layers, aggregating into randomly located blisters, incompatible with scalable fabrication processes. Here we
D. Purdie   +5 more
semanticscholar   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

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