Results 61 to 70 of about 665,037 (318)
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Concepts and issues in interfaces for multiple users and multiple devices [PDF]
In this paper, we identify and discuss several groups of issues that arise in the design of interfaces for multiple users interacting with multiple devices.
Kray, Christian +2 more
core
Navigating telephone-based interfaces with earcons [PDF]
Non-speech audio messages called earcons can provide powerful navigation cues in menu hierarchies. However, previous research on earcons has not addressed the particular problems of menus in telephone-based interfaces (TBI's) such as: Does the lower ...
Brewster, S.A., Stephen Brewster
core +1 more source
Biophysical approaches for studying viral entry
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Although more people are engaging in meditation practices that require specialized training, few studies address the issues associated with nervous activity pattern changes brought about by such training.
Anna Rusinova +2 more
doaj +1 more source
Palladium Thiolate Bonding of Carbon Nanotube Thermal Interfaces
Carbon nanotube (CNT) arrays can be effective thermal interface materials with high compliance and conductance over a wide temperature range. Here, we study CNT interface structures in which free CNT ends are bonded using Pd hexadecanethiolate, Pd(SC(16 ...
G. U. Kulkarni +11 more
core +1 more source
Internal interface diversification with multiple fake interfaces
Malware uses knowledge of well-known interfaces to achieve its goals. However, if we uniquely diversify these interfaces in each system, the malware no longer knows the "language" of a specific system and it becomes much more difficult for malicious programs to operate.
Sampsa Rauti, Ville Leppänen
openaire +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Engineering hybrid perovskites at the molecular level to solve the stability problem remains a challenge. Here Grätzel et al. design a multifunctional molecular modulator that interacts with the perovskite via modes elucidated by solid state NMR ...
Dongqin Bi +10 more
doaj +1 more source

