Results 71 to 80 of about 665,037 (318)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Considering people living with dementia when designing interfaces [PDF]

open access: yes, 2014
Dementia is an escalating problem which is estimated to affect 35.6 million people worldwide. In an environment which is becoming increasingly dependent on technology, the interaction needs of people living with dementia is being ignored by interface ...
Good, Alice   +3 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

CH3NH3PbBr3 is not pyroelectric, excluding ferroelectric-enhanced photovoltaic performance

open access: yesAPL Materials, 2016
To experimentally (dis)prove ferroelectric effects on the properties of lead-halide perovskites and of solar cells, based on them, we used second-harmonic-generation spectroscopy and the periodic temperature change (Chynoweth) technique to detect the ...
Yevgeny Rakita   +7 more
doaj   +1 more source

Perspectives on the design of musical auditory interfaces [PDF]

open access: yes, 1998
This paper addresses the issue of music as a communication medium in auditory human-computer interfaces. So far, psychoacoustics has had a great influence on the development of auditory interfaces, directly and through music cognition.
Brewster, S.A.   +5 more
core  

Constructing digital library interfaces

open access: yes, 2007
The software technologies used to create web interfaces for digital libraries are discussed using examples from Greenstone ...
Nichols, David M.   +5 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Building better solid‐state batteries with silicon‐based anodes

open access: yesInterdisciplinary Materials, 2023
Silicon (Si)‐based solid‐state batteries (Si‐SSBs) are attracting tremendous attention because of their high energy density and unprecedented safety, making them become promising candidates for next‐generation energy storage systems.
Zhefei Sun   +16 more
doaj   +1 more source

Porphyrins at interfaces

open access: yesNature Chemistry, 2015
Porphyrins and other tetrapyrrole macrocycles possess an impressive variety of functional properties that have been exploited in natural and artificial systems. Different metal centres incorporated within the tetradentate ligand are key for achieving and regulating vital processes, including reversible axial ligation of adducts, electron transfer ...
Willi Auwärter   +3 more
openaire   +3 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

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