Results 61 to 70 of about 1,773,910 (282)

Fusion of conformal interfaces [PDF]

open access: yes, 2007
We study the fusion of conformal interfaces in the c=1 conformal field theory. We uncover an elegant structure reminiscent of that of black holes in supersymmetric theories.
Bachas, C., Brunner, I.
core   +3 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Multifunctional molecular modulators for perovskite solar cells with over 20% efficiency and high operational stability

open access: yesNature Communications, 2018
Engineering hybrid perovskites at the molecular level to solve the stability problem remains a challenge. Here Grätzel et al. design a multifunctional molecular modulator that interacts with the perovskite via modes elucidated by solid state NMR ...
Dongqin Bi   +10 more
doaj   +1 more source

Interface Dermatitis

open access: yesArchives of Pathology & Laboratory Medicine, 2008
AbstractInterface dermatitis can be classified based upon the cell type that dominates the infiltrate (ie, neutrophilic, lymphocytic, or lymphohistiocytic) or by the intensity of the interface inflammation. Regarding lymphocytic interface dermatitis, there are 2 broad categories: cell-poor interface dermatitis, when only a sparse infiltrate of ...
A Neil, Crowson   +2 more
openaire   +2 more sources

Evaluating advanced search interfaces using established information-seeking model

open access: yes, 2009
When users have poorly defined or complex goals search interfaces offering only keyword searching facilities provide inadequate support to help them reach their information-seeking objectives.
schraefel, m.c.   +2 more
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Short-term meditation training alters brain activity and sympathetic responses at rest, but not during meditation

open access: yesScientific Reports
Although more people are engaging in meditation practices that require specialized training, few studies address the issues associated with nervous activity pattern changes brought about by such training.
Anna Rusinova   +2 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Building better solid‐state batteries with silicon‐based anodes

open access: yesInterdisciplinary Materials, 2023
Silicon (Si)‐based solid‐state batteries (Si‐SSBs) are attracting tremendous attention because of their high energy density and unprecedented safety, making them become promising candidates for next‐generation energy storage systems.
Zhefei Sun   +16 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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