Results 91 to 100 of about 512,651 (227)

Intrinsic Viral Factors Are the Dominant Determinants of the Hepatitis C Virus Response to Interferon Alpha Treatment in Chimeric Mice.

PLoS ONE, 2016
BackgroundHepatitis C virus infection is a global health problem. New direct-acting antiviral agents have been recently approved. However, due to their high cost and some genotypes remaining difficult to treat, interferon-based therapy with pegylated ...
Ran Chen, Michelle Kobewka, William Addison, Gerald Lachance, D Lorne Tyrrell   +4 more
doaj   +1 more source

Estudio del interferón tipo III sobre la infección del virus del dengue [PDF]

, 2016
"En las enfermedades virales, la infección es controlada en la célula por el interferón tipo I (IFN-α), sin embargo, el virus del dengue (DENV) tiene la capacidad de inhibir esta respuesta. El interferón tipo III, también conocido como interferón lambda (
Palma Ocampo, Helen Kenia, PALMA OCAMPO, HELEN KENIA; 227637   +1 more
core  

Dynamic Loading Regulates Meniscus‐Like Matrix Production in Human Mesenchymal Stromal Cell‐Seeded PET Scaffolds

Advanced Healthcare Materials, EarlyView.
Dynamic compression enhances mesenchymal stromal cell proliferation in nonwoven PET scaffolds under chondrogenic differentiation conditions and triggers mechanosensitive transcriptional programs associated with extracellular matrix remodeling. These findings highlight the potential of mechanically stimulated PET scaffolds as a promising platform for ...
Graciosa Quelhas Teixeira, Luisa de Roy, Anna‐Lotta Feldmeier, Mubashir Ahmad, Sofia Pilão, Maria Ahrens, Anita Ignatius, Carsten Linti, Andreas Martin Seitz   +8 more
wiley   +1 more source

Autoanticuerpos en pacientes hematológicos tratados con interferón alfa

Revista Cubana de Hematología, Inmunología y Hemoterapia
Se estudió la presencia de autoanticuerpos en 45 pacientes con enfermedades hematológicas: 32 con leucemia mieloide crónica (LMC) y 13 con otras enfermedades linfoproliferativas (ELP).
Antonio A Bencomo Hernández, María E Alfonso Valdés, Arturo Munster Infante, Paulino Basanta Otero, Edgardo Espinosa Martínez, Porfirio Hernández Ramírez   +5 more
doaj  

DESARROLLO EMBRIONARIO Y ESTRATEGIAS ANTILUTEOLITICAS HORMONALES EN PROGRAMAS DE TRANSPLANTE DE EMBRIONES BOVINOS [PDF]

Revista Mvz Cordoba, 2008
Durante el desarrollo embrionario se establecen múltiples interacciones entre hormonas, factores de crecimiento (FC) y diferente tipo de moléculas, con lo cual se genera una serie de señales que desencadenan el reconocimiento materno de preñez (RMP ...
Néstor Tovío L, Arturo Duica A, Henry Grajales L   +2 more
doaj  

Water‐Activated Phospholipid Phase‐Separation Gel as an Immunomodulatory Anti‐Adhesion Barrier for Postoperative Adhesion Prevention

Advanced Healthcare Materials, EarlyView.
A water‐activated phospholipid phase‐separation gel is repurposed as a drug‐free surgical barrier for postoperative adhesion prevention. Propylene glycol promotes rapid lamellar gel reinforcement, prolonged local retention, and tissue coverage, while phosphatidylcholine‐mediated immunomodulation suppresses inflammatory and fibrotic responses. This dual‐
Jong‐Ju Lee, Yulseung Sung, Yeji Kim, Heesang Yang, Suyeon Pyo, Byeol Yun, Sung‐Joo Hwang   +6 more
wiley   +1 more source

Establecimiento y validación de un ensayo inmunoenzimático tipo ELISA, empleado en el control de calidad del Interferón alfa 2b humano recombinante

VacciMonitor, 2009
Se estableció y validó un ELISA para la cuantificación del Interferón alfa 2b humano recombinante en el Ingrediente Farmacéutico Activo, definiéndose los criterios de validez del ensayo y basado en el cumplimiento de las Buenas Prácticas de Laboratorio ...
Susset Valderrama, Eliana Pérez, Yurisleydis Aldama, Lourdes Costa, Marisel Quintana, Gudelia Pérez, Gerardo García   +6 more
doaj  

An Engineered Biomimetic Nanoreactor With Cascade Functions for Targeted and Combinatorial Therapy of Ischemic Stroke

Advanced Healthcare Materials, EarlyView.
Preparation of RVG‐modified erythrocyte membrane‐coated HMPB nanocarriers loaded with L‐arginine and NBP (RM@HPAN) and its neuroprotective mechanism. After intravenous injection, RM@HPAN achieves prolonged circulation, RVG‐29‐mediated BBB penetration, and ischemic accumulation.
Shaofa Li, Ying Wu, Huimin Wei, Jinyong Teng, Zaizhi Yang, Jufang Chen, Bao Liao, Xiaoqin Huang, Lanqing Meng, Tong Li   +9 more
wiley   +1 more source

Interferón alfa-2b tópico como primera opción en las neoplasias intraepiteliales corneoconjuntivales

Anales del Sistema Sanitario de Navarra, 2012
Se describen dos casos de neoplasia intraepitlelial corneo-conjuntival (CIN) tratados con interferón alfa- 2b (IFN α-2b) tópico como primera elección.
M. Pérez de Arcelus, M. Aranguren, J. Andonegui   +2 more
doaj  

Anisotropic Masked Mycobacterium Potentiates Amplified Antitumor Trained Immunity via Spleen Targeting and Myelopoiesis Conversion

Advanced Materials, EarlyView.
An engineered Trojan Mycobacterium, developed via a “peeling‐off and masking‐up” strategy, functions as a powerful splenic myelopoiesis converter. This spleen‐targeted nanomedicine induces trained immunity to reprogram immunosuppressive myeloid reservoirs into antitumoral effectors.
Jin‐Ho Choi, Sang Nam Lee, Jang Hun Heo, Soyoung Park, Sei Hyun Park, Yong Taik Lim   +5 more
wiley   +1 more source