Results 71 to 80 of about 512,651 (227)

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian   +6 more
wiley   +1 more source

Intensive Farmaco- Surveillance of Interferon Alpha 2b Recombinant in Multiple Sclerosis.

open access: yesMedisur, 2007
Background: The interferon alpha 2b recombinant, produced in Cuba, is used in the treatment of different illnesses, such as the multiple sclerosis. For its commercialization it is needed to know its safety scope.
Leslie Pérez Ruiz   +4 more
doaj   +2 more sources

Sarcoidosis tras tratamiento con interferón y ribavirina. Presentación de un caso y revisión de la bibliografía

open access: yes, 2004
El tratamiento con interferón alfa en la hepatitis crónica activa por el virus C tiene una eficacia demostrada, por ello se está generalizando su uso a gran número de pacientes. Entre los efectos secundarios, las manifestaciones respiratorias banales son
Pérez Ronchel, José   +5 more
core  

Disease Course After Anti‐CD20 Discontinuation in Secondary Progressive Multiple Sclerosis—A Multicenter Long‐Term Longitudinal Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To describe long‐term outcomes after anti‐CD20 discontinuation in selected patients with secondary progressive multiple sclerosis (SPMS) who remained without subsequent disease‐modifying therapy (DMT). Methods We retrospectively analyzed data from four centers in Austria and Switzerland.
Ferdinand Otto   +12 more
wiley   +1 more source

Neoplasia intraepitelial conjuntival. Interferón como terapia de rescate tras fracaso de la mitomicina C

open access: yes
Varón de 60 años con lesión conjuntival diagnosticada de neoplasia intraepitelial corneal conjuntival (NICC), iniciándose tratamiento con mitomicina C. Tras 3 semanas y mínima mejoría, se reemplaza por interferón alfa 2B. Seis meses después, con completa
Duch Samper, Antonio Miguel   +3 more
core   +1 more source

Tiroiditis autoinmune inducida por interferón en pacientes con infección por virus de la hepatitis C

open access: yes, 2011
A 43 year old man presented with asymptomatic elevation of alanine aminotransferase (ALT) and no relevant past history. The patient denied being a chronic alcohol drinker.
Pinto, Miguel E., Pinto, José L.
core   +1 more source

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong   +10 more
wiley   +1 more source

Infección aguda por el VHC

open access: yesAnales del Sistema Sanitario de Navarra, 2008
La infección aguda por el virus C de la hepatitis produce un cuadro clínico y bioquímico no específico e indistinguible de los causados por otros virus hepatotropos.
A. Martínez Echeverría   +3 more
doaj  

Tratamiento de las Neoplasias Mieloproliferativas BCR-ABL1 Negativas (NMP). Experiencia Personal con Interferón y Comentarios sobre Nuevas Drogas

open access: yes, 2021
Encouraged by the benefits of interferon on CML and by the absence of leukemogenic effect on PV, we started using it in the late 1980s. Eight patients with PV were treated with conventional IFN-alpha2b and, although effective to induce remissions with ...
Musso, Arturo
core  

“Low‐Positive” MOG‐IgG Cases Among Adults With a First Event Suggestive of Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the prevalence and clinical characteristics of patients with “low‐positive” (LP) MOG‐IgG (titres 1:160–1:320) among adults with a first demyelinating event (FDE) suggestive of multiple sclerosis (MS). Methods From the Barcelona CIS inception cohort, we included adult patients with serum collected ≤ 6 months from the FDE.
Javier Villacieros‐Álvarez   +29 more
wiley   +1 more source

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