Results 51 to 60 of about 491,602 (238)

Results of interferon-based treatments in Alaska Native and American Indian population with chronic hepatitis C [PDF]

International Journal of Circumpolar Health, 2016
Background: There have been few reports of hepatitis C virus (HCV) treatment results with interferon-based regimens in indigenous populations. Objective: To determine interferon-based treatment outcome among Alaska Native and American Indian (AN/AI ...
Stephen E. Livingston, Lisa J. Townshend-Bulson, Dana J. T. Bruden, Chriss E. Homan, James E. Gove, Julia N. Plotnik, Brenna C. Simons, Philip R. Spradling, Brian J. McMahon   +8 more
doaj   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Costo-efectividad del tratamiento con interferón beta en pacientes con síndrome clínico aislado de alto riesgo en Colombia

, 2014
Introducción. En 85 % de los pacientes con esclerosis múltiple se presenta como manifestación inicial un primer evento desmielinizante o síndrome clínico aislado.
Zarco, Luis Alfonso, Taborda Restrepo, Alejandra, Millán, Sonia Patricia, Londoño Trujillo, Darío, Sonia Patricia Millán, Ludy Parada, Parada Vargas, Ludy Alexandra, Millán Pérez, Sonia Patricia, Darío Londoño, Miguel Germán Borda, Zarco Montero, Luis Alfonso, Borda, Miguel Germán, Parada, Ludy, Taborda, Alejandra, Luis Alfonso Zarco, Borda Borda, Miguel German, Londoño, Darío, Alejandra Taborda   +17 more
core   +1 more source

Virus B e interferón

Acta Médica Costarricense, 2008
La aparición de nuevas drogas y formas de diagnóstico, han transformado la hepatitis crónica B de una enfermedad fatal a una manejable y aún curable. Se distinguen dos tipos de enfermedad crónica por virus B, la que se desarrolla con antígeno e positivo ...
Gerardo Avendaño-Alvarado
doaj  

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Utilidad de los ensayos de liberación de interferón gamma para la detección de tuberculosis en población pediátrica

, 2015
El ensayo de liberación de interferón gamma es un método novedoso para el diagnóstico de la tuberculosis aunque su utilidad es incierta en población pediátrica.
Jehan Bonizú Álvarez-Meza, Manuel Alberto Cano-Rangel, María del Carmen Candía-Plata, Enrique Bolado-Martínez, Miriam Denisse García-Villa, María de los Ángeles Durazo-Arvizu, Luis Fernando López-Soto, Gerardo Álvarez-Hernández   +7 more
core   +1 more source

Sistema interferón y estrés oxidativo

Revista Cubana de Investigaciones Biomédicas, 2001
Los interferones forman parte de una familia de proteínas que ejercen efectos biológicos diversos. En el caso particular del interferón, se encuentra involucrado en el proceso inflamatorio y la producción de especies reactivas del oxígeno.
Massiel Rosario Quijano, José C García Piñeiro   +1 more
doaj  

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Different effects of rat interferon alpha, beta and gamma on rat hepatic stellate cell proliferation and activation

BMC Cell Biology, 2002
Background Liver fibrosis is the common sequel of chronic liver diseases. Recent studies have identified hepatic stellate cells as the primary cell type mediating hepatic fibrogenesis.
Minuk Gerald Y, Zhang Manna, Shen Hong, Gong Yuewen   +3 more
doaj   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source