Results 161 to 170 of about 512,651 (227)

Molecular Response, Event-Free Survival, and Treatment-Free Remission in Myeloproliferative Neoplasms: Update and Review with Insights from MPN Asia 2026. [PDF]

Curr Hematol Malig Rep
Abu-Zeinah G, Hobbs GS, Rampal RK, Lee SE, Gill H, Komrokji R, Tashi T, Bose P, Mascarenhas J, Yacoub A, Oh ST, Shimoda K, Reeves BN, Duan M, Yu LH, Qin A, Prchal JT, Kaushansky K, Mesa RA.   +18 more
europepmc   +1 more source

Pasta, a Versatile Transcriptomic Clock, Maps the Chemical and Genetic Determinants of Aging and Rejuvenation

Advanced Science, EarlyView.
Pasta is a transcriptomic aging clock built on an age‐shift learning framework and trained on 17 000 samples across 21 datasets. It accurately predicts relative biological age across tissues, platforms, and species, captures stemness‐to‐senescence transitions, and identifies age‐modulatory perturbations.
Jérôme Salignon, Maria Tsiokou, Patricia Marqués, Enriqueta Rodríguez‐Diaz, Hazel Ang, Federico Pietrocola, Christian G. Riedel   +6 more
wiley   +1 more source

Type I interferon in psoriasis: mechanisms and clinical implications. [PDF]

Front Immunol
Liu C, Zhang Y, Cui X, Zhang H, Chen J, Lian X, Yang S.   +6 more
europepmc   +1 more source

Desarrollo normal del embarazo en dos pacientes con leucemia mieloide crónica tratadas con interferón-a

La leucemia mieloide crónica (LMC) es un trastorno clonal que generalmente se diagnostica con facilidad porque las células leucémicas en más del 95 % de los pacientes presentan una anomalía citogenética característica, el cromosoma Filadelfia (Ph).
María L Telles-Chacón, Onel M Avila-Cabrera, Edgardo Espinosa-Estrada, Leslie González-Pinedo, Carlos Hernández-Padrón, Lissette Izquierdo-Cano, Wilfredo Roque-García, Luis G Ramón-Rodríguez, Gelquin Mustelier-Celza   +8 more
core  

Nanovesicles With Mechanically Induced Adjuvanticity for Robust Melanoma Vaccination Toward Tumor‐Associated Macrophages

Advanced Science, EarlyView.
Rigidity‐tunable nanovesicle (P‐Pm) with mechanically induced adjuvanticity toward tumor‐associated macrophages (TAMs) was designed to engineer R848/gp100 antigen ‐loaded nanovaccine (P@Rg‐Pm), which achieved outstanding anti‐tumor outcomes in both therapeutic and preventive model of B16‐F10 melanoma.
Bangyue Luo, Liyan Qiu
wiley   +1 more source

Comparative innate immune responses across major RNA and DNA viral infections: Mechanisms, immunopathology, and therapeutic perspectives. [PDF]

Hum Vaccin Immunother
Mashhadi Abolghasem Shirazi M.
europepmc   +1 more source

Autoimmunity and peginterferon therapy for polycythemia vera. [PDF]

Hemasphere
Rivière E, Guy A, Mansier O, Mediavilla C, Kiladjian JJ, James C, Blanco P, Lazaro E, Viallard JF.   +8 more
europepmc   +1 more source

AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing

Advanced Science, EarlyView.
A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li, Haojie Fu, Zhe Wang, Xuanzhou Chen, Ruhong Zhang, Xudong Wang, Louis D. Zhang, Xiang Li, Datao Li   +8 more
wiley   +1 more source

Köhlmeier-Degos disease is an interferonopathy characterized by type I and II interferon-driven inflammatory vasculopathy. [PDF]

Cell Rep Med
Cudrici CD, Goel S, Sakamoto K, Jin SP, Sekiguchi A, Rosing DR, Huffstutler R, Hammoud DA, Shapiro L, Schwartz DM, Manohar-Sindhu S, Taylor ME, Zhang Y, Schaughency P, Cowen EW, Hasni S, Kaplan MJ, Kong HH, Boehm M, Nagao K.   +19 more
europepmc   +1 more source

Rocket‐Inspired Sequentially Targeted Nanotherapeutics for Mitochondrial Regulation and Inflammatory Reprogramming in Ischemic Stroke

Advanced Science, EarlyView.
A novel neutrophil‐hitchhiking, rocket‐inspired nanoplatform is developed to cross the blood‐brain barrier for sequential, spatiotemporal drug delivery. By responsive surface transformation in the ischemic penumbra, it precisely targets mitochondria to suppress Drp1‐mediated fission.
He Bai, Zihao Yong, Yang Li, Qingmin Chen, Yong Liu, Xiaomeng Guo, Fukai Li, Shicheng Tang, Zhuo Yang, Yufei Zhang, Ruwei Jie, Xiaohong Lv, Huacheng Wang, Chunming Huang, Liwei Xie, Jianqi Xiao, Qingchun Mu, Longguang Tang   +17 more
wiley   +1 more source