Results 81 to 90 of about 379,902 (266)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Interference Alignment for the K-User MIMO Interference Channel [PDF]

IEEE Transactions on Information Theory, 2010
25 pages, 4 figures, Presented in part at ISIT 2010, submitted to IEEE Transactions on Information Theory, June ...
Akbar Ghasemi, Abolfazl Seyed Motahari, Amir Keyvan Khandani   +2 more
openaire   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Interference Mitigation in Large Random Wireless Networks [PDF]

, 2011
A central problem in the operation of large wireless networks is how to deal with interference -- the unwanted signals being sent by transmitters that a receiver is not interested in. This thesis looks at ways of combating such interference.
Aldridge, Matthew
core  

Maximum-rate Transmission with Improved Diversity Gain for Interference Networks

, 2013
Interference alignment (IA) was shown effective for interference management to improve transmission rate in terms of the degree of freedom (DoF) gain. On the other hand, orthogonal space-time block codes (STBCs) were widely used in point-to-point multi ...
Jafarkhani, Hamid, Li, Liangbin
core   +2 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Joint alignment and steering to manage interference

Digital Communications and Networks
In wireless communication networks, mobile users in overlapping areas may experience severe interference, therefore, designing effective Interference Management (IM) methods is crucial to improving network performance.
Zhao Li, Xiujuan Liang, Yinghou Liu, Jia Liu, Zheng Yan   +4 more
doaj   +1 more source

Fractional Interference Alignment: An Interference Alignment Scheme for Finite Alphabet Signals

, 2013
Interference Alignment (IA) is a transmission scheme which achieves 1/2 Degrees-of-Freedom (DoF) per transmit-antenna per user. The constraints imposed on the scheme are based on the linear receiver since conventional IA assumes Gaussian signaling.
Ram, B Hari, Giridhar, K
openaire   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

CSI Feedback Reduction for MIMO Interference Alignment

, 2013
Interference alignment (IA) is a linear precoding strategy that can achieve optimal capacity scaling at high SNR in interference networks. Most of the existing IA designs require full channel state information (CSI) at the transmitters, which induces a ...
Lau, Vincent K. N., Rao, Xiongbin, Ruan, Liangzhong   +2 more
core   +2 more sources