Results 91 to 100 of about 146,198 (337)
A selection of statistically stable (robust) algorithms for data variance calculating has been made. Their properties have been analyzed via computer simulation.
Baan +21 more
core +1 more source
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
The development of telecommunications technology has shown a dynamic trend, especially with the emergence of 5G mobile technology. Indonesia, a developing country with high connectivity needs, has allocated frequencies for 5G services, including the ...
Alfin Hikmaturokhman +4 more
doaj +1 more source
Matlab- Based Interference Mitigation in WPAN IR-UWB
Impulse Radio - Ultra Wideband (IR-UWB) is a wireless technology system that offers a high data rate within a short range. Therefore, IR-UWB system is regarded as an excellent physical layer solution to the multi-piconet Wireless Personal Area Network ...
Abbas Saleh Hassan
doaj +1 more source
Self-Interference Cancellation Using Time-Domain Phase Noise Estimation in OFDM Full-Duplex Systems
In full-duplex systems, oscillator phase noise (PN) problem is considered the bottleneck challenge that may face the self-interference cancellation (SIC) stage especially when orthogonal frequency division multiplexing (OFDM) transmission scheme is ...
Khattab, Tamer, Shehata, Heba
core +1 more source
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
This paper presents an adaptive interference mitigation scheme for multiple coexisting wireless body area networks (WBANs) based on social interaction. The proposed scheme considers the mobility of nodes within each WBAN as well as the relative movement ...
Samaneh Movassaghi +4 more
doaj +1 more source

