Results 81 to 90 of about 20,175 (250)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Interference mitigation in intentional jammers aided non-uniform heterogeneous cellular networks. [PDF]

PLoS One, 2023
Ghonaim SM, Khan S, Althobiani F, Alghaffari S, Khan S, Irfan M, Haroon MS, Muhammad F.   +7 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Robust Interference Mitigation in GNSS Snapshot Receivers

Navigation
The robust interference mitigation (RIM) framework offers a promising solution to jamming attacks on global navigation satellite system (GNSS) receivers. By identifying interfered samples as outliers in the selected transform domain, RIM operates without
Helena Calatrava, Adrià Gusi-Amigó, Floor Melman, Pau Closas   +3 more
doaj   +1 more source

Half-duplex and full-duplex interference mitigation in relays assisted heterogeneous network. [PDF]

PLoS One, 2023
Madani Fadoul M, Chow CO.
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Emerging Interference Modeling and Analysis Techniques for 6G Networks: A Comprehensive Survey

IEEE Access
As the evolution towards 6G networks accelerates, key technologies such as extremely large MIMO (XL-MIMO), reconfigurable intelligent surfaces (RIS), and integrated sensing and communication (ISAC) are anticipated to play an important role. The emergence
Jung-Bum Lee, Gyung-Eun Kim, Hyunduk Kang, Ho-Kyung Son, Woong-Hee Lee   +4 more
doaj   +1 more source

Wide-Band Interference Mitigation in GNSS Receivers Using Sub-Band Automatic Gain Control. [PDF]

Sensors (Basel), 2022
van der Merwe JR, Garzia F, Rügamer A, Urquijo S, Contreras Franco D, Felber W.   +5 more
europepmc   +1 more source