Results 81 to 90 of about 26,616 (287)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Investigation of Blanking Nonlinearity in OFDM Systems

open access: yes, 2011
In this paper, we analyze the influence of a blanking nonlinearity onto OFDM systems in detail. We will derive closedform expressions for the signal degradation and the interference, which is introduced by the blanking nonlinearity.
Michael Schnell   +5 more
core   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Spectrum Management and Interference Mitigation Between 5G and Satellite Services on Extended C-Band and mmWave: Enhancing National Revenue

open access: yesIEEE Access
The development of telecommunications technology has shown a dynamic trend, especially with the emergence of 5G mobile technology. Indonesia, a developing country with high connectivity needs, has allocated frequencies for 5G services, including the ...
Alfin Hikmaturokhman   +4 more
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Efficient Intercarrier Interference Mitigation for Pilot-Aided Channel Estimation in OFDM Mobile Systems

open access: yes, 2011
Motivated by the possibility of decreasing the intersymbol interference (ISI) which is due to large delays of a multipath mobile radio channel, orthogonal frequency division multiplexing (OFDM) became very popular. However, the timevariance of the mobile
Groh, Ingmar, Dammann, Armin
core  

Matlab- Based Interference Mitigation in WPAN IR-UWB

open access: yesWasit Journal of Engineering Sciences, 2015
Impulse Radio - Ultra Wideband (IR-UWB) is a wireless technology system that offers a high data rate within a short range. Therefore, IR-UWB system is regarded as an excellent physical layer solution to the multi-piconet Wireless Personal Area Network ...
Abbas Saleh Hassan
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Interference mitigation techniques in wireless communications systems

open access: yes, 2011
Co-Channel Interference, Intersymbol interference and fading are major impairment to the high-capacity transmission in power- and band-limited wireless communication channel.
Oyedepo, JA   +5 more
core   +1 more source

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