Results 71 to 80 of about 20,175 (250)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Enabling interference-aware and energy-efficient coexistence of multiple wireless body area networks with unknown dynamics

IEEE Access, 2016
This paper presents an adaptive interference mitigation scheme for multiple coexisting wireless body area networks (WBANs) based on social interaction. The proposed scheme considers the mobility of nodes within each WBAN as well as the relative movement ...
Samaneh Movassaghi, Akbar Majidi, Abbas Jamalipour, David Smith, Mehran Abolhasan   +4 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Methods for GNSS Interference Mitigation Using Wavelet Transform and Spatial Signal Processing

Известия высших учебных заведений России: Радиоэлектроника
Introduction. An analytical review of literature sources reporting various methods for GNSS interference mitigation using wavelet transform and signal processing in spatial and space–time domains is conducted.
K. Yu. Kolomensky
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Nonlinear Chirp Interference Mitigation in Snapshot GNSS Receivers Using Piecewise Least Squares Estimation With Fractional Fourier Transform

IEEE Journal of Indoor and Seamless Positioning and Navigation
Global Navigation Satellite Systems (GNSSs) face increasing vulnerability to radio frequency interference, with chirp signals representing a particularly challenging threat due to their time-varying frequency characteristics that disrupt receivers across
Xavier Alvarez-Molina, Gonzalo Seco-Granados, Jose A. Lopez-Salcedo   +2 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Wideband Array Signal Processing with Real-Time Adaptive Interference Mitigation. [PDF]

Sensors (Basel), 2023
Whipple A, Ruzindana MW, Burnett MC, Kunzler JW, Lyman K, Jeffs BD, Warnick KF.   +6 more
europepmc   +1 more source