Results 51 to 60 of about 939,916 (257)
Simulation of Multi-element Antenna Systems for Navigation Applications [PDF]
The application of user terminals with multiple antenna inputs for use with the global satellite navigation systems like GPS and Galileo becomes more and more attraction in last years.
Denks, Holmer +3 more
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Interference mitigation techniques in wireless communications systems
Co-Channel Interference, Intersymbol interference and fading are major impairment to the high-capacity transmission in power- and band-limited wireless communication channel.
Oyedepo, JA +5 more
core +1 more source
L-DACS1 Laboratory Demonstrator Development and Compatibility Measurement Set-up [PDF]
The Future Communications Infrastructure (FCI) comprises a set of data link technologies for aeronautical communications. For the airport, a data link technology dubbed AeroMACS is currently developed within NextGen and SESAR which is strongly based on ...
Franzen, Nico +5 more
core +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Cooperative Downlink Multicell Preprocessing Relying on Reduced-Rate Back-Haul Data Exchange [PDF]
Different-complexity multicell preprocessing (MCP) schemes employing distributed signal-to-interference leakage-plus-noise ratio (SILNR) precoding techniques are proposed, which require reduced back-haul data exchange in comparison with the conventional ...
Rong Zhang +3 more
core +1 more source

