Results 101 to 110 of about 448,902 (332)
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
机车电传动, 2022 According to the complexity of electromagnetic interference of traction system of high-speed EMU, and in combination with the design of the vehicle system, the EMI coupling paths of traction system were analyzed.
YANG Deyong +5 more
doaj
ElectronicsWith the advancement of electromagnetic interference and counter-interference technology, complex and unpredictable interference signals greatly reduce radar detection, tracking, and recognition performance. In multi-interference environments, the overlap of interference cross-correlation peaks can mask target signals, weakening radar interference ...
Rui Cai, Chenge Shi, Wei Dong, Ming Bai
openaire +1 more source
End-to-End Autoencoder Communications with Optimized Interference Suppression [PDF]
, 2021 Kemal Davaslıoğlu +2 more
openalex +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
IET Science, Measurement & TechnologyThe co‐frequency co‐time full duplex (CCFD) system transmits and receives signals at the same frequency simultaneously, which can effectively improve the communication spectrum utilization of satellite and solve the problem of satellite frequency ...
Yuting Zhang +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
International Journal of Antennas and Propagation, 2017 Interference suppression techniques have been intensively studied in nearly two decades due to their importance for maintaining the integrity and functionality of global navigation satellite system (GNSS).
Qiang Guo, Liangang Qi
doaj +1 more source
Side Lobe Suppression in NC-OFDM Systems Using Variable Cancellation Basis Function
IEEE Access, 2017 In non-continuous orthogonal frequency division multiplexing (NC-OFDM)-based cognitive radio system, the sidelobe suppression methods use the fixed length rectangular windowing functions for canceling carriers (CCs) like the extended active interference ...
Shaik Yasmin Fathima +4 more
doaj +1 more source