Results 81 to 90 of about 27,952 (237)

Label‐Free Holographic Imaging Flow Cytometry With Deep‐Learning‐Based Detection and Classification of Thousands of Cells Per Second

Cytometry Part A, EarlyView.
ABSTRACT We present a new end‐to‐end neural network approach for real‐time biological cell detection and classification via label‐free quantitative imaging flow cytometry based on digital holography, offering a comprehensive representation of cellular structures without the need for chemical cell staining. In contrast to previous studies, our method is
Dana Yagoda‐Aharoni, Eden Dotan, Matan Dudaie, Natan T. Shaked   +3 more
wiley   +1 more source

Traceable Refractive Index Measurements of Liquids to Standardize Extracellular Vesicle Flow Cytometry

Cytometry Part A, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are potential disease biomarkers released by cells into body fluids. Flow cytometers measure EV concentrations within their size detection range. These size ranges can be quantified by relating the arbitrary units of measured light scattering signals to the optical diameter of EVs with Mie theory.
Martine Kuiper, Richard Koops, Rienk Nieuwland, Ton G. van Leeuwen, Edwin van der Pol   +4 more
wiley   +1 more source

Research progress and current status of dynamic wave propagation characteristics in rock mass: A review

Deep Underground Science and Engineering, EarlyView.
This review elucidates the velocity–dispersion–attenuation coupling mechanisms of wave propagation in rock masses, compares six representative models, and reveals how pressure, temperature, mineral composition, and anisotropy jointly control dynamic responses in complex geological media.
Jiajun Shu, Tao Li, Ruiqi Yuan, Yue Li, Bingni Wu, Bo Liu, Zhengding Deng, Galindo Rubén, Fausto Molina‐Gómez   +8 more
wiley   +1 more source

Nanomaterials and Eco‐Friendly Refrigerants in Vapor Compression System: A Review of Performance and Sustainability

Energy Science &Engineering, EarlyView.
This review highlights how nano oils and eco‐friendly nano refrigerants enhance energy‐efficient refrigeration by improving thermal conductivity, lubrication, and system performance. The integration of rheological and tribological testing confirms reduced compressor work, better heat transfer, and higher COP using sustainable, low‐GWP refrigerants for ...
Mohammed Dilawar, Bisma Ali, Turali Narayana, Mohammad Reza Chalak Qazani, Rehan Khan, Adnan Qayoum, Tabrez Qureshi, Mohd Mujtaba Ahmed   +7 more
wiley   +1 more source

Research progress on the use of the optical coherence tomography system for the diagnosis and treatment of central nervous system tumors

Ibrain, Volume 11, Issue 1, Page 3-18, Spring 2025.
With the advantages of high‐resolution imaging, efficient image acquisition, intraoperative real‐time detection, and radiation‐free and noninvasive characteristics, optical coherence tomography (OCT) provides accurate diagnosis and effective intraoperative guidance for the minimally invasive diagnosis and treatment of central nervous system (CNS ...
Jiuhong Li, Ziba Ayi, Gonggong Lu, Haibo Rao, Feilong Yang, Jing Li, Jiachen Sun, Junlin Lu, Xulin Hu, Si Zhang, Xuhui Hui   +10 more
wiley   +1 more source

Coherence evaluation and first demonstration of multi-contrast X-ray computed tomography on NanoTerasu BL09W with an X-ray Talbot interferometer. [PDF]

J Synchrotron Radiat
Coherence properties were evaluated and multi‐contrast X‐ray computed tomography was demonstrated using an X‐ray Talbot interferometer on the NanoTerasu beamline BL09W. The results confirm the high spatial coherence and imaging performance of the source, paving the way for advanced X‐ray phase imaging.We report on the coherence evaluation of the ...
Ueda R, Liang X, Kamezawa C, Sumiishi H, Bishago Y, Nishio T, Yoshida J, Daimon M, Hiramoto S, Voegeli W, Shirasawa T, Vagovič P, Yamane H, Nakamura T, Yashiro W.   +14 more
europepmc   +2 more sources

Construction of a clickable probe‐based protein chip platform for discovering covalent mIDH1 inhibitors from natural medicinal extracts

iMeta, EarlyView.
In this study, we develop a flexible Ccc‐Chip (protein microarray + bioorthogonal click chemistry) for high‐throughput screening of natural covalent active molecules from medicinal plant extracts, identifying flavokawain C from Piper methysticum Forst as a novel covalent mIDH1 inhibitor.
Zhao Cui, Jiameng Li, Caifeng Li, Mo Sun, Wei Liu, Xuxia Cao, Shiwen Deng, Junxian Cao, Hongjun Yang, Peng Chen   +9 more
wiley   +1 more source

Inhibition of ferroptosis by microbiota‐derived lithocholic acid underlies the intestinal radioprotection of a host defensin‐derived oligopeptide

iMeta, EarlyView.
AT9(C/G), an oligopeptide derived from human defensin 5, enriches Bifidobacterium pseudolongum and increases lithocholic acid (LCA) levels in the intestine. Reduced levels of LCA link to increased severity of ionizing radiation‐induced intestinal injury (IRIII) in both murine and clinical studies.
Xue Ouyang, Yingjuan He, Zihao Jin, Shaobo Wang, Gaomei Zhao, Xiaona Su, Jia Du, Yin Chen, Chengzhang Tan, Xin Li, Songling Han, Bin Wang, Jinghong Zhao, Jianqin Niu, Chuan Chen, Junping Wang, Cheng Wang   +16 more
wiley   +1 more source

Targeting DGKα/PA axis inhibits tumor immune evasion and augments sensitivity to immunotherapy in gastrointestinal cancers

iMeta, EarlyView.
Immune checkpoint inhibitors (ICIs) have shown promising antitumor efficacy in certain types of solid tumors. However, the efficacy of ICIs remains unsatisfactory owing to the dysregulation of signaling pathways in local tumor tissues. Here, we reveal that diacylglycerol kinase α (DGKα)‐derived phosphatidic acid (PA) directly binds to nuclear factor‐κB
Jie Chen, Siqi Liu, Ting Peng, Fenglong Wang, Yuheng Zhu, Jingyuan Pang, Qingnan Wu, Yan Wang, Qimin Zhan   +8 more
wiley   +1 more source

Amplification of Light‐Ultrasound Interaction in a Pi‐Shifted Fiber Bragg Grating for Enhanced Ultrasonic Sensitivity

Laser &Photonics Reviews, EarlyView.
By precisely engineering the geometry of a fiber‐based optical resonator, the interaction between confined light and external ultrasound waves is significantly amplified without sacrificing light confinement, boosting the ultrasound detection sensitivity beyond 0.5 mPa/√Hz.
Tai‐Anh La, Rami Shnaiderman, Vasilis Ntziachristos   +2 more
wiley   +1 more source