Results 191 to 200 of about 236,190 (268)

MiR‐146a‐5p Suppresses M1 Polarization of Tumor‐Associated Macrophages via IRAK1/NF‐κB Signaling in Colorectal Polyps

Annals of Gastroenterological Surgery, EarlyView.
MiR‐146a‐5p is downregulated in colorectal polyps, leading to IRAK1 upregulation and NF‐κB activation, which promotes M1 macrophage polarization and inflammation. Overexpression of miR‐146a‐5p suppresses IRAK1/NF‐κB signaling, reduces M1 polarization, and alleviates inflammatory responses.
Peng Song, Lianhui Wu, Huabin Qiu, Lei Luo, Jianzhao Qiu, Shuping Xiao, Jincai He   +6 more
wiley   +1 more source

Expression levels of interleukin-17 and interferon-γ in peripheral blood and relationship with thyroid function in patients with Hashimoto's thyroiditis. [PDF]

Front Mol Biosci
Huang Z, Zhang J, Chen S, Mao M, Wang B.
europepmc   +1 more source

POEMS Syndrome: 2026 Update on Diagnosis, Risk‐Stratification, and Management

American Journal of Hematology, EarlyView.
ABSTRACT Disease Overview POEMS syndrome is a life‐threatening syndrome due to an underlying plasma cell neoplasm. The major criteria for the syndrome are polyneuropathy, clonal plasma cell disorder (PCD), sclerotic bone lesions, elevated vascular endothelial growth factor, and the presence of Castleman disease.
Angela Dispenzieri
wiley   +1 more source

Associations of Schistosoma mansoni Infection, Latent Tuberculosis, Host Interferon-γ Concentrations, and Praziquantel Treatment in Tanzanian Adults. [PDF]

Am J Trop Med Hyg
Pham K, Miyaye E, Ward M, Mukerebe C, Ulomi N, Moshi S, Mhango L, Lutonja P, de Jong D, van Dam G, Corstjens PLAM, Fitzgerald DW, Peck RN, Downs JA, Jaka H.   +14 more
europepmc   +1 more source

Immune Modulatory Therapy for Severe Dengue Hemorrhagic Fever in a Patient With Mitochondrial Complex I Deficiency: A Case Report

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Dengue virus (DENV) poses a serious global health challenge, particularly in cases of dengue hemorrhagic fever (DHF). Patients with preexisting mitochondrial disorders may be at increased risk for complications due to the specific impact of DENV on mitochondrial‐dependent cellular processes and immune function.
Audra N. Iness, Ameya S. Walimbe, Emily R. Strouphauer, Michio Hirano, Alejandro D. Iglesias, Valentina Emmanuele, Caitlin C. Griffin, Sheldon L. Kaplan, William A. Gomes, Karen K. Moeller, Stephen F. Kralik, Fernando Scaglia   +11 more
wiley   +1 more source

Attenuated interferon-γ following injury is associated with chronic critical illness. [PDF]

J Trauma Acute Care Surg
Cuschieri J, Kornblith LZ, Kalthoum H, Cuschieri S, Pati S, Piliponsky A.   +5 more
europepmc   +1 more source

Tezepelumab in Chinese Patients With Severe Chronic Rhinosinusitis With Nasal Polyps: A Prespecified Subgroup Analysis of the Phase 3 WAYPOINT Trial

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) in Chinese patients often exhibits a mixed Type 1/2/3 inflammatory phenotype (63%), potentially impacting the efficacy of biologics targeting Type 2 inflammation. This prespecified subgroup analysis of WAYPOINT (NCT04851964) evaluated the efficacy and safety of tezepelumab in Chinese
Li Hu, Houyong Li, Xicai Sun, Quan Liu, Yu Xu, Jiangang Fan, Andrew Foster, Claudia Chen, Yun Chon, Dehui Wang   +9 more
wiley   +1 more source

Interferon-γ orchestrates leptomeningeal anti-tumour response. [PDF]

Nature
Remsik J, Tong X, Kunes RZ, Li MJ, Estrera R, Snyder J, Thomson C, Osman AM, Chabot K, Sener UT, Wilcox JA, Isakov D, Wang H, Bale TA, Chaligné R, Sun JC, Brown C, Pe'er D, Boire A.   +18 more
europepmc   +1 more source

Correlation of Local Nasal Biomarkers and Olfactory Dysfunction in Chronic Rhinosinusitis: A Systematic Review and Meta‐Analysis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background To systematically evaluate the local biomarkers correlated with olfactory dysfunction (OD) in chronic rhinosinusitis (CRS). Methods A systematic review was conducted in CINAHL, Cochrane Library, PubMed, and Scopus from inception to July 2025.
David Kayekjian, Neeti Gandra, Shaun A. Nguyen, Shaina W. Twardus, Rodney J. Schlosser   +4 more
wiley   +1 more source

Quantitative analysis of interferon-γ and interleukin-4 levels in serum and saliva of oral lichen planus patients. [PDF]

Natl J Maxillofac Surg
Chaurasia A, Patil RK, Kaushik S, Ali W, Tiwari R, Heller D.   +5 more
europepmc   +1 more source