Results 111 to 120 of about 230,357 (266)

Impact of Alpha Interferon and Ribavirin on the Function of Maturing Dendritic Cells

, 2004
Eleanor Barnes, Mariolina Salio, Vincenzo Cerundolo, Joanne Medlin, Shona Murphy, Geoffrey Dusheiko, Paul Klenerman   +6 more
openalex   +1 more source

In Situ Engineering of Tumor Cells as Self‐Sustaining cDC1 Programming Factories for Effective Cancer Immunotherapy

Advanced Science, EarlyView.
The fused EV platform AS16‐EL@MPLA/p‐FX reprograms tumor cells into cytokine‐producing factories that continuously secrete XCL1 and FLT3L to recruit and differentiate cDC1s, while embedded MPLA activates them through TLR4 signaling and AS16 prevents their exhaustion, thereby enhancing antitumor immunity and establishing durable immune memory against ...
Shuiling Jin, Xiaoxi Wang, Bingyu Li, Xueqin Zhu, Zimai Liu, Jiao Lu, Yuanyuan Wei, Zixian Wu, Kai Li, Tiantian Zhang, Zonghong He, Pingping Zhu, Yuanming Qi, Benyu Liu, Hui Liu, Yongchao Wang, Zhenzhen Chen   +16 more
wiley   +1 more source

Nanoparticle‐Modified Nanofibers Induce Ferroptosis and Stimulate Antitumor Immunity for Melanoma Therapy

Advanced Science, EarlyView.
This study presents a nanoparticle‐embedded nanofiber (5F/STFM/R‐ES) to inhibit melanoma growth and reduce the risk of metastasis and recurrence. The drug delivery system induces ferroptosis and potentiates immunotherapy through resiquimod (R848) and Fe/Mn‐based metal‐polyphenol networks (TFM).
Mingyang Li, Rongrong Li, Baotong Xu, Yuhan Lian, Chenyu Yang, Jingwen Li, Junhao Liang, Linhan Ding, Dongsheng Zhang, Jing Guo, Xiao Fu   +10 more
wiley   +1 more source

Evaluation of Cu containing amine oxidase is sera of gastric cancer patients [PDF]

Introduction: Cupper containing amine oxidase (Cu-AO) catalyzes the deamination of primary amines to corresponding aldehydes in the presence of oxygen with the subsequent release of ammonia and hydrogen peroxide.
اتحاد, غلامحسین, امانی, مجتبی, برزگر, ابوذر, یزدانبد, عباس   +3 more
core  

Association between anti-interferon-alpha autoantibodies and COVID-19 in systemic lupus erythematosus [PDF]

, 2020
Sarthak Gupta, Shuichiro Nakabo, Jun Chu, Sarfaraz Hasni, Mariana J. Kaplan   +4 more
openalex   +1 more source

Tumor‐Derived Interleukin 35 Promotes Fibrosis in the Tumor Microenvironment of Pancreatic Cancer by Activating Pancreatic Stellate Cells

Advanced Science, EarlyView.
This study demonstrates that tumor‐derived IL‐35 promotes pancreatic cancer fibrosis by indirectly activating pancreatic stellate cells through IGFBP2/IGF‐1R/PI3K‐Akt and Tsp‐1/TGF‐β pathways. IL‐35 blockade reduces stromal fibrosis, restores chemosensitivity, and synergizes with gemcitabine‐based regimens, highlighting IL‐35 as a promising therapeutic
Hui Li, Huizhi Sun, Jing Liu, Yan Wu, Lin Wei, Jianming Li, Yudong Yuan, Peng Xie, Chao Xu, Guolu Luo, Yuqi Guan, Yukuan Feng, Antao Chang, Jihui Hao, Chongbiao Huang   +14 more
wiley   +1 more source

Ultrasensitive Test Systems Are Required to Quantify Interferon Alpha Protein in Serum Samples. [PDF]

Eur J Immunol
Haljasmägi L, Meisalu S, Bondet V, Peterson P, Duffy D, Kisand K.   +5 more
europepmc   +1 more source

Biochemical characterization of the membrane-associated phosphorylating proteins involved in the anti-proliferative effect of human recombinant interferon-alpha 2a (rIFN-.ALPHA.2a) in daudi cells.

, 1990
Minehiko Yokoyama, Kaori Koike, Shin-ichiro Kanno, Kenzo Ohtsuki   +3 more
openalex   +2 more sources

Wedelolactone, a Novel TLR2 Agonist, Promotes Neutrophil Differentiation and Ameliorates Neutropenia: A Multi‐Omics Approach to Unravel the Mechanism

Advanced Science, EarlyView.
Wedelolactone (WED), a natural TLR2 agonist, promotes neutrophil differentiation and enhances bactericidal function, offering a potential therapeutic strategy for neutropenia. Using a multi‐omics approach, this study reveals that WED activates the TLR2/MEK/ERK pathway, upregulating key transcription factors (PU.1, CEBPβ) to drive neutrophil development.
Long Wang, Zhichao Li, Tianci Hu, Qinyao Li, Linwei Zhang, Xinyue Mei, Xiao Qi, Sheng Liu, Weijie Kong, Jiesi Luo, Anguo Wu, Feihong Huang, Sirui Li, Shuang Dai, Chunxiang Zhang, Rong Li, Jianming Wu   +16 more
wiley   +1 more source

How I do it: continuous intraventricular interferon alpha infusion in pediatric patients with subacute sclerosing panencephalitis. [PDF]

Acta Neurochir (Wien)
Tengattini F, Errichiello G, Varone A, Cinalli G, Ruggiero C.   +4 more
europepmc   +1 more source