CD8+ Lymphocytes from Healthy Blood Donors Secrete Antiviral Levels of Interferon-Alpha
The adaptive immune response to viral infections features the antigen-driven expansion of CD8+ T cells. These cells are widely recognized for their cytolytic activity that is mediated through the secretion of cytokines such as perforin and granzymes ...
Fernando Teque +3 more
doaj +1 more source
Liver-Targeting of Interferon-Alpha with Tissue-Specific Domain Antibodies [PDF]
PMCID: PMC3581439This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
A Trahtenherts +45 more
core +15 more sources
Purpose: To describe the clinical course of a patient presenting with unilateral retinopathy after perilesional interferon alpha injections for treatment of ocular surface squamous cell carcinoma.
Shiv Dalla +4 more
doaj +1 more source
Production and Characterization of Polyclonal Antibodies Against Interferon Alpha in Mice
The polyclonal antibodies are used extensively for research purposes in many areas of biology, such as immunoprecipitation, histochemistry, enzyme linked immunosorbent assays (ELISA), diagnosis of disease and western blots. Typically, an animal’s immune
Mehreen Fatima +2 more
doaj +1 more source
Interferon alpha-induced reduction in the values of myeloid-derived suppressor cells in melanoma patients [PDF]
Background/Aim. Interaction between tumor cells and host’s immunoregulatory cells in creation of microenvironment that supports tumor progression is the focus of numerous investigations in recent years.
Stanojević Ivan +11 more
doaj +1 more source
Schwannoma response to interferon alpha
While cranial nerve schwannomas are typically benign, slow growing tumors, they are associated with morbidity both from the neuropathies and neuralgias they can produce, as well as from the treatments used to address these tumors, typically surgery or ...
Jennifer Novak +2 more
doaj +1 more source
Adding low-dose antidepressants to interferon alpha treatment for chronic hepatitis C improved psychiatric tolerability in a patient with schizoaffective psychosis [PDF]
Treatment of chronic hepatitis C with interferon alpha (IFN-alpha) is relatively contraindicated in patients with psychiatric disorders because of possible severe psychiatric side effects.
Amann, B. +5 more
core +1 more source
This review article provides a general perspective of the experimental and clinical work surrounding the role of type-I, type-II, and type-III interferons (IFNs) in the pathophysiology of brain and spinal cord injury. Since IFNs are themselves well-known
Francesco Roselli +4 more
doaj +1 more source
Retreatment with interferon-alpha and ribavirin in primary interferon-alpha non-responders with chronic hepatitis C [PDF]
Background/Aims: Combination therapy with interferon-alpha (IFN-alpha) plus ribavirin is more efficacious than IFN-alpha monotherapy in previously untreated patients with chronic hepatitis C and patients with IFN-alpha relapse.
Berg, Thomas +8 more
core +1 more source
Pegylated interferon-alpha-2a for the treatment of ocular surface squamous neoplasia
Ocular surface squamous neoplasia (OSSN) is the most common nonpigmented ocular surface neoplasm. Interferon-alpha (IFNα)-2b has been proved to be an effective immunotherapeutic agent to treat OSSN.
Murtuza Nuruddin +2 more
doaj +1 more source

