Interferon Alpha Association with Neuromyelitis Optica
Clinical and Developmental Immunology, 2013 Interferon-alpha (IFN-α) has immunoregulatory functions in autoimmune inflammatory diseases. The goal of this study was to determine occurrence and clinical consequences of IFN-α in neuromyelitis optica (NMO) patients.
Nasrin Asgari +5 more
doaj +1 more source
The sustained virologic response of nonresponder hepatitis C virus patients with retreatment
Indian Journal of Pathology and Microbiology, 2011 Background: Pegylated interferon and ribavirin combination therapy remain the first-line treatment for chronic hepatitis C virus (HCV) infection. In contrast to the large number of studies in treatment-naive patients, the effectiveness of retreatment in ...
Sila Cetin Akhan +2 more
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Use of Pegylated Interferon Alpha-2a in Cutaneous T-cell Lymphoma: A Retrospective Case Collection
Acta Dermato-Venereologica, 2023 Mycosis fungoides and Sézary syndrome are rare and largely incurable types of cutaneous T-cell lymphoma with limited therapeutic options. In 1984 Bunn et al.
Janika Gosmann +4 more
doaj +1 more source
Retinal Changes In Patients with Hepatitis C Virus under treatment with interferon and ribavirin. [PDF]
Egyptian Journal of Medical Research, 2020 Background: Chronic Hepatitis C is common problem worldwide treated by combination of interferon alpha and ribavirin. Retinopathy is one of the side effects of interferon therapy.
Mansour Hassan +3 more
doaj +1 more source
Acute Hepatitis Induced by Alpha-Interferon in a Patient with Chronic Hepatitis C
Canadian Journal of Gastroenterology, 2001 Hepatic adverse effects occur very rarely with alpha-interferon therapy. A case of acute hepatitis induced by alpha-interferon in a 33-year-old man with chronic hepatitis C is described.
Ivan Kraus, Dinko Vitezic
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New approaches and therapeutic modalities for the treatment of patients with chronic hepatitis C
Annals of Hepatology, 2005 A major challenge in the field of hepatology is the fight against hepatitis C that affects more than 150 million people world-wide. Despite the enormous improvement that has been achieved in the therapy of chronic hepatitis C over the last decade, there ...
Markus Cornberg, Michael P. Manns
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THE IMMUNOCOMPETENT CELLS RECEPTORS RESEARCH UNDER EXPERIMENTAL INFLUENZA INFECTION IN VITRO
Инфекция и иммунитет, 2015 Introduction. It is known that interferon is a cytokine and is a substantial part of the immune system necessary for antigenic challenge immune response full expression. Also it is considered that every antigen is an interferon inducer.
A. N. Lisakov +6 more
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Тhe prophylactic efficacy of a recombinant interferon alfa-2b drug in children with bronchial asthma
Детские инфекции (Москва), 2019 A prospective cohort study was conducted to assess the effect of a recombinant interferon alpha-2b prophylactic course on cyto-immunological parameters of induced sputum in children with mild asthma, the main trigger of exacerbation of which was ...
Y. I. Zhakov +2 more
doaj +1 more source
IFNα-mediated remodeling of endothelial cells in the bone marrow niche
Haematologica, 2017 In the bone marrow, endothelial cells are a major component of the hematopoietic stem cell vascular niche and are a first line of defense against inflammatory stress and infection.
Áine M. Prendergast +5 more
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source