Results 11 to 20 of about 1,152,600 (293)

Transcriptional responses of tumor cell lines to interferon-alpha [PDF]

, 2013
Interferon is an antiviral and antiproliferative cytokine therapeutically applied to treat hepatitis infection and cancer expansion. The beneficial effects of interferon-alpha are dependent on efficient signaling by activation of defined JAK-STAT pathway
Siegrist, Fredy
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Retreatment with interferon-alpha and ribavirin in primary interferon-alpha non-responders with chronic hepatitis C [PDF]

, 2000
Background/Aims: Combination therapy with interferon-alpha (IFN-alpha) plus ribavirin is more efficacious than IFN-alpha monotherapy in previously untreated patients with chronic hepatitis C and patients with IFN-alpha relapse.
Leifeld, Ludger, Spengler, Ulrich, Hoffmann, Robert M., Berg, Thomas, Hopf, Uwe, Pape, Gerd R., Teuber, Gerlinde, Lafrenz, Michael, Zeuzem, Stefan, Gerd R. Pape, Stefan Zeuzem, Ludger Leifeld, Ulrich Spengler, Robert M. Hoffmann, Michael Lafrenz, Uwe Hopf, Gerlinde Teuber, Thomas Berg   +17 more
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Adding low-dose antidepressants to interferon alpha treatment for chronic hepatitis C improved psychiatric tolerability in a patient with schizoaffective psychosis [PDF]

, 2000
Treatment of chronic hepatitis C with interferon alpha (IFN-alpha) is relatively contraindicated in patients with psychiatric disorders because of possible severe psychiatric side effects.
Amann, B., Schmidt, F., Schlösser, S., Loeschke, K., Grunze, Heinz, Schäfer, Martin   +5 more
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Interferon signalling in the liver : implications for the natural course and therapy of hepatitis C [PDF]

, 2012
Hepatitis C virus is a global health concern, estimated to infect 2-3% of the world's population. Inter-individual differences in the course of infection and response to therapy, highlighted by recent genomewide association studies, point to the crucial ...
Makowska, Zuzanna
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Comparison of the Effects of Early Pregnancy with Human Interferon, Alpha 2 (IFNA2), on Gene Expression in Bovine Endometrium [PDF]

, 2012
Interferon tau (IFNT), a type I IFN similar to alpha IFNs (IFNA), is the pregnancy recognition signal produced by the ruminant conceptus. To elucidate specific effects of bovine IFNT and of other conceptus-derived factors, endometrial gene expression ...
Sax, Gerhard, Minten, Megan, Winter, Gerhard, Büttner, Mathias, Reichenbach, Horst-Dieter, Wolf, Eckhard, Meyer, Heinrich H. D., Bauersachs, Stefan, Reichenbach, Myriam, Spencer, Thomas E., Ulbrich, Susanne E.   +10 more
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Activation of PKR by Bunyamwera virus is independent of the viral interferon antagonist NSs [PDF]

, 2003
Double-stranded RNA (dsRNA) is a by-product of viral RNA polymerase activity, and its recognition is one mechanism by which the innate immune system is activated.
Boyd, A., Boyd, A, Fazakerley, John K., Weber, F, Elliott, Richard M., Fazakerley, John K, Weber, Friedemann, Weber, F., Streitenfeld, Hein, J. K. Fazakerley, Elliott, Richard M, Boyd, Amanda, H. Streitenfeld, Elliott, R.M., Streitenfeld, H., A. Bridgen, Bridgen, A., Streitenfeld, H, Fazakerley, J K, Fazakerley, J.K., F. Weber, R. M. Elliott, Bridgen, A, Elliott, Richard Michael, Bridgen, Anne, A. Boyd   +25 more
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The regulation of type I interferon production by paramyxoviruses [PDF]

, 2009
Research supported by The Wellcome Trust (087751/A/08/Z)Experimentally, paramyxoviruses are conventionally considered good inducers of type I interferons (IFN-alpha/beta), and have been used as agents in the commercial production of human IFN-alpha ...
Goodbourn, S, Richard E. Randall, Stephen Goodbourn, Randall, Richard Edward   +3 more
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Epstein-Barr Virus LF2: an Antagonist to Type 1 Interferon [PDF]

, 2009
Upon viral infection, the major defense mounted by the host immune system is activation of the interferon (IFN)-mediated antiviral pathway, which is mediated by IFN regulatory factors (IRFs).
Shin, Young Chul, Johannsen, Eric, Haas, Juergen, Hyun Joo, Chul, Fossum, Even, Hutt-Fletcher, Lindsay M., Wu, L., Inn, Kyung-Soo, Jung, Jae U.   +8 more
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Genome-wide expression profiling identifies type 1 interferon response pathways in active tuberculosis [PDF]

, 2012
Contains fulltext : 108027.pdf (Publisher’s version ) (Open Access)Tuberculosis (TB), caused by Mycobacterium tuberculosis (M.tb), remains the leading cause of mortality from a single infectious agent.
Crevel, R. van, van Crevel, R., Hazel E E Wong, Sahiratmadja Edhyana, Zhang, M.M., Wong, Hazel EE, Ottenhoff, THM, van de Vosse, Esther, Yang, N., Ottenhoff, T.H., Martin L Hibberd, Ottenhoff Tom H. M., Khor C.C., Dass, Ranjeeta, Reinout van Crevel, Hibberd M.L., van Crevel Reinout, Dass R.H., Yang, N, Chiea Chuen Khor, Khor, C.C., Seielstad, M., Zhang Mingzi M., van de Vosse E., Zhang M.M., Ottenhoff, Tom HM, Tom H M Ottenhoff, van Crevel, Reinout, Ottenhoff, T.H.M., Yang, Ninghan, Sahiratmadja, Edhyana, Wong, H.E., Seielstad M., Sahiratmadja E., Alisjahbana Bachti, Marzuki, Sangkot, van Crevel R., Khor, CC, Edhyana Sahiratmadja, Bachti Alisjahbana, Yang Ninghan, Alisjahbana, B., Hibberd, M.L., Ninghan Yang, Alisjahbana, Bachti, van, R, van de Vosse, E., Wong, Hazel, Dass Ranjeeta Hari, Alisjahbana, B, Ranjeeta Hari Dass, Hibberd, Martin, Yang, N.H., Sangkot Marzuki, Dass, Ranjeeta Hari, Seielstad Mark, Khor Chiea Chuen, Ottenhoff, Tom, Marzuki, S., Dass, RH, Hibberd Martin L., Marzuki, S, Wong H.E.E., Marzuki S., Zhang, M.Z.M., Zhang, MM, Khor, Chiea, van de Vosse Esther, Khor, Chiea Chuen, Mark Seielstad, Vosse, E. van de, Marzuki Sangkot, Sahiratmadja, E., Dass, R.H., Yang N., Zhang, Mingzi, Seielstad, Mark, Wong, HEE, Hibberd, Martin L, Sahiratmadja, E, Ottenhoff T.H.M., Zhang, Mingzi M, Esther van de Vosse, Alisjahbana B., Wong Hazel E. E., Wong, H.E.E., Mingzi M Zhang   +86 more
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Proliferative retinopathy in a diabetic on interferon therapy: A diagnostic dilemma

Kerala Journal of Ophthalmology, 2016
Hepatitis C virus (HCV) is a blood-borne RNA virus that causes hepatitis C, chronic liver disease, and hepatocellular carcinoma. Patients with HCV infection are now treated with a combination of interferon alpha, which has antiviral and immunomodulatory ...
Prajina Rahul, Manoj Venugopal, S Sija, R S Dhanya, Elizabeth John   +4 more
doaj   +1 more source