Results 131 to 140 of about 236,225 (308)

Two distinct families of human and bovine interferon-alpha genes are coordinately expressed and encode functional polypeptides.

, 1985
Daniel J. Capon, H. Michael Shepard, David V. Goeddel   +2 more
openalex   +2 more sources

EFFICACY OF INTERFERON ALPHA IN THE TREATMENT OF CHILDREN WITH CHRONIC HEPATITIS B [PDF]

, 1990
M Ruíz-Moreno, Maria José Rua, Jaime García-aguado, J. Ouiroga, Juan Carlos Porres, Gloria Moraleda, V. Carreño   +6 more
openalex   +1 more source

A Patient‐Derived Organ‐on‐Chip Platform for Modeling the Tumor Microenvironment and Drug Responses in Pancreatic Cancer

Advanced Science, EarlyView.
Researchers have developed a patient‐derived organ‐on‐a‐chip model for pancreatic cancer by integrating cancer cells with supportive stromal and immune cells inside a microfluidic device. This system mimics the tumor microenvironment, enabling personalized testing of chemotherapy and immunotherapy, and offering new insights into how targeting ...
Darbaz Adnan, Natan Roberto de Barros, Luca S. Santovito, Xuhong Cheng, Kristi M. Lawrence, Mariah K. Barnett, Martine D. Boetto, Neal Mehta, Ajaypal Singh, Lin Cheng, Xiangsheng Huang, Faraz Bishehsari   +11 more
wiley   +1 more source

Alpha interferon (2b) in combination with zidovudine for the treatment of presymptomatic feline leukemia virus-induced immunodeficiency syndrome

, 1990
N. S. Zeidner, Matthew H. Myles, Candace K. Mathiason, Matthew J. Dreitz, James I. Mullins, Edward A. Hoover   +5 more
openalex   +2 more sources

Wedelolactone, a Novel TLR2 Agonist, Promotes Neutrophil Differentiation and Ameliorates Neutropenia: A Multi‐Omics Approach to Unravel the Mechanism

Advanced Science, EarlyView.
Wedelolactone (WED), a natural TLR2 agonist, promotes neutrophil differentiation and enhances bactericidal function, offering a potential therapeutic strategy for neutropenia. Using a multi‐omics approach, this study reveals that WED activates the TLR2/MEK/ERK pathway, upregulating key transcription factors (PU.1, CEBPβ) to drive neutrophil development.
Long Wang, Zhichao Li, Tianci Hu, Qinyao Li, Linwei Zhang, Xinyue Mei, Xiao Qi, Sheng Liu, Weijie Kong, Jiesi Luo, Anguo Wu, Feihong Huang, Sirui Li, Shuang Dai, Chunxiang Zhang, Rong Li, Jianming Wu   +16 more
wiley   +1 more source

Tumor Necrosis Factor Alpha and Gamma Interferon are Required for the Development of Protective Immunity to Secondary Corynebacterium pseudotuberculosis Infection in Mice.

, 1999
Đinh Thị Bích Lân, Sou‐ichi Makino, Toshikazu Shirahata, Manabu Yamada, Akio Nakane   +4 more
openalex   +2 more sources

Characterization of regulatory (interferon-alpha/beta) and accessory (LAF/IL 1) monokine activities from liver granuloma macrophages of Schistosoma mansoni-infected mice. [PDF]

, 1987
David E. Elliott, V F Righthand, Dov L. Boros   +2 more
openalex   +1 more source

The Osteoblastic Microenvironment Determines the Fate of Breast Cancer Cells Disseminated in the Bone Marrow

Advanced Science, EarlyView.
This study revealed how the osteoblastic microenvironment determines the fate of cancer cells disseminated in bone, with a focus on whether they colonize, reside in quiescence, or reactivate from dormancy. Targeting integrin signaling may offer promising strategies for preventing quiescent cancer cells reactivation and bone colonization.
Hong‐Li Wang, Rui Zhang, Xiao‐Min Yue, Jie Zhou, Yu‐Fan Huang, Rong Meng, Yu‐Li Wang, Xiao‐Qing Li   +7 more
wiley   +1 more source

B. C. G. plus recombinant interferon α2b in superficial bladder cancer

Indian Journal of Urology, 2001
We have studied the efficacy of adjuvant therapy in the form of low dose B.C.G. and interferon alpha 2b. In the present study 7patients with superficial bladder car-cinoma (6 recurrent and I primary) have been treated by TURBT and intravesical ...
Gyan Prakash Singh, Usha Singh, U S Diwedi, P B Singh   +3 more
doaj  

Does the interferon-lambda rather than the interferon-alpha pathway determine the outcome of hepatitis C virus infection? [PDF]

, 2014
Sabine Mihm, U. Spengler, Ahmad Amanzada, Giuliano Ramadori   +3 more
openalex   +1 more source