Results 131 to 140 of about 203,970 (332)

Activation of HTR2B Suppresses Osteosarcoma Progression through the STAT1‐NLRP3 Inflammasome Pathway and Promotes OASL1+ Macrophage Production to Enhance Antitumor Immunity

Advanced Science, EarlyView.
Activation of HTR2B suppresses osteosarcoma progression through the STAT1‐NLRP3 inflammasome pathway and promotes OASL1+ Macrophage production to enhance anti‐tumor immunity. Abstract Osteosarcoma is a primary malignant bone tumor originating from mesenchymal tissue, and associated with poor prognosis.
Zhen Huang, Jiazhuang Zhu, Jianping Hu, Xingkai Wang, Xiaolong Ma, Enjie Xu, Kunpeng Zhu, Chunlin Zhang   +7 more
wiley   +1 more source

Sugar Functionalized Collagen Material for Local Modulation of Innate Immunity

Advanced Science, EarlyView.
Modulation of the innate immune response at the implant site can significantly influence adaptive immunity. A mannose‐functionalized collagen patch, termed the Local Immunotuning Patch (LIP), has been designed to engage mannose receptors on antigen‐presenting cells while exhibiting antibacterial properties. LIP orchestrates complex immune pathways that
Francesca Taraballi, Claudia Corbo, Julia Enterria‐Rosales, John Otto Martinez, Silvia Minardi, Laura Pandolfi, Xing Wang, Ennio Tasciotti, Kavindra V. Singh, Cesar A. Arias, Bruna Corradetti   +10 more
wiley   +1 more source

FREQUENCY OF SIDE EFFECTS OF ANTIVIRUS THERAPY FOR CHRONIC VIRUS HEPATITIS IN CHILDHOOD

Педиатрическая фармакология, 2010
In pediatrics, the issue of using antivirus therapy for chronic virus hepatitis is not sufficiently studied, there is search for rational combinations, schemes, doses and length of treatment. The article demonstrates results of using a combined antivirus
S.V. Romanova, E.A. Zhukova, N.A. Kaplina, L.V. Korkotashvili, I.V. Mayanskaya, M.V. Groshovkina, I.A. Timchenko   +6 more
doaj   +2 more sources

Agonist and antagonist effects of interferon alpha and beta on activation of human macrophages. Two classes of interferon gamma receptors and blockade of the high-affinity sites by interferon alpha or beta. [PDF]

, 1988
Ryotaro Yoshida, Henry W. Murray, Carl Nathan   +2 more
openalex   +1 more source

Pyruvate Carboxylase in Macrophages Aggravates Atherosclerosis by Regulating Metabolism Reprogramming to Promote Inflammatory Responses Through the Hypoxia‐Inducible Factor‐1 Signaling Pathway

Advanced Science, EarlyView.
This study investigates the role of macrophage pyruvate carboxylase (PC) in atherosclerosis (AS) demonstrating that PC upregulation in macrophages promotes metabolism reprogramming to enhance inflammatory responses via the HIF‐1 signaling pathway.
Ling‐Na Zhao, Rui‐Ling Wang, Ran‐Xin Liu, Meng‐Ru Zheng, Li Zhao, Bao‐Feng Li, Jia‐Le Li, De‐Shen Liu, Xiao‐Xia He, Qin‐Bao Peng, Kai Li, Tian‐Xiao Lin, Ying‐Ying Liu, Sheng‐Ping He, Jun Lu, Shao‐Yi Zheng, Xiu Liu, Fang‐Ze Huang   +17 more
wiley   +1 more source

Molecular characterization, tissue expression, and antiviral activities of Bama minipig interferon-α subtypes

Heliyon
Interferons play a major role in innate immunity and disease resistance. Porcine interferon alpha has 17 subtypes, and their gene sequences, tissue expression profiles, and antiviral activities have been primarily studied in domestic pigs but not in ...
Aziz Ullah Noor, Lu Huipeng, Zhanyu Du, Song Chengyi, Zhou Xiaohui, Liu Xiaoming, Suliman khan, Huaichang Sun, Abdelouahab Bellou   +8 more
doaj  

Interferon-alpha treatment for chronic hepatitis C in children

The Turkish Journal of Pediatrics, 2000
Interferon-alpha therapy has been proven efficient in chronic hepatitis C infection. Although it has been used as a standard therapy in adults, there are limited data on benefits of interferon treatment in children.
A Yüce, N Koçak, F Gürakan, H Ozen
doaj  

In vitro sensitivity testing of human renal cell carcinoma with cytostatic agents and interferon alpha-2a [PDF]

, 1991
AC Buzaid, AR Hanauske, AW Hamburger, C. G. Stief, DD Hoff Von, DT Harris, E. Allhoff, G Kovacs, G. Lenis, HB Muss, J Gerdes, J Gerdes, J Gerdes, J Rinehart, JB Kernion de, JL Cordell, JP Bergerat, JU Gutterman, LD Leder, M Albrecht, MM Lieber, P. Anton, PHM Mulder de, R. Schlick, RT Oliver, S. Liedke, SD Fossa, U. Jonas, W Riese de, W Riese de, W. de Riese, WH Davis, WJ Hrushesky   +32 more
core   +1 more source

Activation of neonatal and adult human macrophages by alpha, beta, and gamma interferons [PDF]

, 1985
Christopher B. Wilson, Judith Westall
openalex   +1 more source

Red Blood Cell‐Induced Bacterial Margination Improves Microbial Hemoadsorption on Engineered Cell‐Depleted Thrombi, Restoring Severe Bacteremia in Rats

Advanced Science, EarlyView.
A highly efficient extracorporeal device for treating bacteremia is developed by integrating microfluidic bacterial margination and engineered cell‐depleted thrombi strategically constructed in the device. The rodent models, severely infected with antibiotic‐resistant bacteria, recover from bacteremia after two subsequent extracorporeal blood ...
Bong Hwan Jang, Su Hyun Jung, Seyong Kwon, Sung Jin Park, Joo H. Kang   +4 more
wiley   +1 more source