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Tumor dsDNA released by cryoablation is taken up by macrophages, activating the cGAS‐STING signaling pathway. This leads to an expansion of the CXCL10+ macrophage pool and increased secretion of CXCL10, which in turn recruits CXCR3+ T cells from draining lymph nodes into the tumor microenvironment to exert anti‐tumor effects.
Xinxin Zhi +17 more
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Results of Response-Guided Therapy with Pegylated Interferon Alpha 2a in Chronic Hepatitis B and D. [PDF]
Gherlan GS +8 more
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Intralesional interferon alpha-2b as a novel treatment for periocular squamous cell carcinoma in horses. [PDF]
Martabano BB +6 more
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Deletion of gE in Herpes Simplex Virus 1 Leads to Increased Extracellular Virus Production and Augmented Interferon Alpha Production by Peripheral Blood Mononuclear Cells. [PDF]
Claeys M +4 more
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TGFB2 mRNA Levels Prognostically Interact with Interferon-Alpha Receptor Activation of IRF9 and IFI27, and an Immune Checkpoint LGALS9 to Impact Overall Survival in Pancreatic Ductal Adenocarcinoma. [PDF]
Qazi S, Trieu V.
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Construction of viral-based expression vectors for high-level production of human interferon alpha 2b in plants. [PDF]
Sindarovska Y, Kuchuk M.
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Pharmacology & Therapeutics, 1995
The alpha-interferons (IFN-alpha) belong to a family of polypeptides comprising several subtypes. Using recombinant DNA technology, it has been possible to create IFN hybrids that provide novel combinations of the amino acid residues from the parental protein sequences.
M A, Horisberger, S, Di Marco
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The alpha-interferons (IFN-alpha) belong to a family of polypeptides comprising several subtypes. Using recombinant DNA technology, it has been possible to create IFN hybrids that provide novel combinations of the amino acid residues from the parental protein sequences.
M A, Horisberger, S, Di Marco
openaire +2 more sources

