Results 211 to 220 of about 1,206,341 (327)

A Biofabricated Human Acinus‐on‐a‐Chip Unveils Mechanotransductive Drivers of Ventilator‐Induced Lung Injury via Decoupling Volutrauma and Barotrauma

Advanced Science, EarlyView.
This bioinspired acinus‐on‐a‐chip recapitulates VILI pathology, revealing that volutrauma drives P53/NF‐κB pathways while barotrauma triggers mitochondrial‐Wnt dysregulation. A fibrotic transitional cell cluster was identified. Pharmacological interventions targeting these pathways significantly ameliorated injury, establishing a mechanobiological ...
Heng Lu, Liansheng Liu, Zengyong Hu, Shuxian Fang, Ruohan Ren, Sidi Liu, Meng Zhao, Zhiting Luo, Ziyue Zhang, Wenlong Shao, Qian Liu   +10 more
wiley   +1 more source

Quantitative interferon gamma responses to Mycobacterium tuberculosis in a community-based survey of adolescents and adults in Blantyre, Malawi

Phiri MD, Rickman HM, Mandalasi C, Chirambo A, Jambo KC, Mwandumba HC, Corbett EL, Horton KC, Henrion MY, MacPherson P.   +9 more
europepmc   +1 more source

Maternal Immune Stimulation With Interferon-Gamma Limits Embryonic Valproic Acid Induced Apoptotic Gene Expression. [PDF]

Birth Defects Res
Frascella D, Mallela MK, Cullen R, Hrubec TC.   +3 more
europepmc   +1 more source

Overcoming Drug Resistance by Paclitaxel Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
In the murine triple‐negative breast cancer (TNBC) model, chemotherapy effectively increases tumor neoantigen burden (TNB). Here, the study constructs a liposomal nanovaccine using antigens derived from in vitro chemotherapy‐treated paclitaxel‐resistant TNBC 4T1 cells.
Bo Chen, Yangyi Wang, Tingting Li, Changqing Guo, Zhe Xie, Zhixian Zhang, Xinghua Han, Wei Wang, Jian Wang, Xiaopeng Ma, Yuanzeng Min   +10 more
wiley   +1 more source

Tracheobronchial infectious diseases in adult-onset immunodeficiency with anti-interferon-gamma autoantibodies. [PDF]

BMC Infect Dis
Liang X, Ma N, Liang S, Huang X, Liang H, Wu S, Ning Y, Pang H, Zhang Z, Chen N, Hong L, He Z.   +11 more
europepmc   +1 more source

Supplementary Table S2 from Interferon Gamma Induces Higher Neutrophil Extracellular Traps Leading to Tumor-Killing Activity in Microsatellite Stable Colorectal Cancer

Hao‐Wei Teng, Tean-Ya Wang, Chun‐Chi Lin, Zhen-Jie Tong, Hsiao-Wei Cheng, Hsiang‐Tsui Wang   +5 more
openalex   +1 more source

Targeting β2‐Adrenergic Receptor Stability With Lycorine Reveals a Host‐Directed Pathway for Antiviral Defense Against Poxviruses

Advanced Science, EarlyView.
Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang, Shuqin Xu, Zixuan Zhang, Chenwen Wan, Xiaoqin Wang, Peihua Wang, Huini Yang, Tianxiao Huang, Yijia Yuan, Faiza Atique, Rui Yang, Yingli He, Zhijun Liu   +12 more
wiley   +1 more source

T-Cell Interferon Gamma Responses to SARS-CoV-2 Following Infection with/Without Vaccination in a Tanzanian Population. [PDF]

Infect Drug Resist
Nkinda L, Barabona G, Ndubi M, Motozono C, Nkuwi E, Kamori D, Msafiri F, Kunambi PP, Osati E, Kidenya BR, Chuwa H, Hassan FE, Kisuse J, Mfinanga S, Senkoro M, Ueno T, Lyamuya EF, Balandya E.   +17 more
europepmc   +1 more source

Supplementary Table S1 from Interferon Gamma Induces Higher Neutrophil Extracellular Traps Leading to Tumor-Killing Activity in Microsatellite Stable Colorectal Cancer

Hao‐Wei Teng, Tean-Ya Wang, Chun‐Chi Lin, Zhen-Jie Tong, Hsiao-Wei Cheng, Hsiang‐Tsui Wang   +5 more
openalex   +1 more source

Beyond Charge: Field‐Effect Transistors in Multimodal Biosensing Platforms for Biomolecular Interaction Studies

Advanced Electronic Materials, EarlyView.
This review summarizes the developments in field‐effect transistor (FET)‐based dual‐mode sensor platforms and what can be learned from them. It identifies charge as a crucial factor in biomolecular interactions at interfaces, outlines the challenges of hybrid systems, and highlights their benefits.
Roger Hasler, Ciril Reiner‐Rozman, Christoph Kleber, Jakub Dostalek, Wolfgang Knoll   +4 more
wiley   +1 more source