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Interferon-Gamma and Mycobacterial Infections
Annals of Internal Medicine, 1988Excerpt Murray's recent review (1) provides a welcome discussion of the role of interferon-gamma as an immune activator of macrophages against microbial pathogens.
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Structure and Effects of Interferon-Gamma
Oncology, 2009This brief overview of the structure of interferon-γ (IFN-γ) and its biological activities emphasizes recent results with recombinant human and murine IFNs and compares this type IIIFN with the type I IFN-α and IFN-β. The amino acid sequence of human IFN-γ is presented. Its antiviral activity and cytostatic or cytotoxic effects are described.
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Interferon-gamma-inhibitory oligodeoxynucleotides alter the conformation of interferon-gamma.
Molecular pharmacology, 1998The aptamer mechanism of action involves the direct interaction of oligonucleotide with protein and is responsible for the biological effects of many pharmacologically active oligodeoxynucleotides. In the work reported here, we have determined the effects of aptamers on the secondary, tertiary, and quaternary structures of the proteins with which they ...
V, Balasubramanian +3 more
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