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The Therapeutic potential of interferon-gamma in tuberculosis [PDF]

open access: yesADMET and DMPK, 2022
Tuberculosis is one of the critical health problems worldwide. The search for ways to improve the results of tuberculosis treatment and overcome drug resistance lies in understanding the pathogenesis of the development of the infectious process.
Svetlana A. Berns   +2 more
doaj   +2 more sources

Interferon-gamma inhibits influenza A virus cellular attachment by reducing sialic acid cluster size

open access: yesiScience, 2022
Summary: The mucosal antiviral role of type I and III interferon in influenza virus infection is well established. However, much less is known about the antiviral mechanism of type II interferon (interferon-gamma).
Carol Ho-Yan Fong   +7 more
doaj   +1 more source

Novel approach to activity evaluation for release-active forms of anti-interferon-gamma antibodies based on enzyme-linked immunoassay. [PDF]

open access: yesPLoS ONE, 2014
Selection of a suitable assay to measure the activity of drug agents based on release-active forms of anti-interferon-gamma antibodies (RA forms of Abs) is an important step forward in the investigation of such agents.
Elena S Gavrilova   +5 more
doaj   +1 more source

Molecular characterization of the 3'-UTRsequence of the interferon-gamma gene and its expression profile in the ocular conjunctiva of amazon buffaloes [PDF]

open access: yesIraqi Journal of Veterinary Sciences, 2023
Interferon-gamma is an important innate immunomodulatory inflammatory cytokine, whose molecular characterization can demonstrate how this gene may or may not be conserved in populations throughout the evolutionary process.
Laura J. Paredes   +8 more
doaj   +1 more source

Evaluation of the Performance of Widal Slide Agglutination Test Compared to Blood Culture and Evaluation of Interferon Gamma Response in the Diagnosis of Typhoid Fever

open access: yesUMYU Journal of Microbiology Research, 2020
Typhoid fever remains a significant public health challenge in developing countries, including Nigeria. The Widal test, widely used for diagnosing typhoid fever due to its simplicity and quick turnaround time, has raised concerns regarding its ...
Mujahid, N. S.   +6 more
doaj   +1 more source

Interferon-γ Inhibits Ebola Virus Infection.

open access: yesPLoS Pathogens, 2015
Ebola virus outbreaks, such as the 2014 Makona epidemic in West Africa, are episodic and deadly. Filovirus antivirals are currently not clinically available.
Bethany A Rhein   +11 more
doaj   +1 more source

Open‐Label Pilot Study of Interferon Gamma–1b in Patients With Non‐Infantile Osteopetrosis

open access: yesJBMR Plus, 2022
The only treatment currently available for patients with severe infantile osteopetrosis is hematopoietic cell transplantation (HCT). HCT‐related toxicity and mortality risks typically preclude its use in non‐infantile patients, and other therapies are ...
Andrew Nguyen   +8 more
doaj   +1 more source

Circulating Interferon-Gamma Levels Are Associated with Low Body Weight in Newly Diagnosed Kenyan Non-Substance Using Tuberculosis Individuals

open access: yesInterdisciplinary Perspectives on Infectious Diseases, 2016
Although interferon-gamma, interleukin-10, and adiponectin are key immunopathogenesis mediators of tuberculosis, their association with clinical manifestations of early stage disease is inconclusive.
Nathan Shaviya   +3 more
doaj   +1 more source

PERAN INTERFERON GAMMA PADA INFEKSI MYCOBACTERIUM TUBERCULOSIS

open access: yesJKS (Jurnal Kedokteran Syiah Kuala), 2018
Abstrak. Penyakit tuberkulosis masih tetap merupakan masalah kesehatan yang utama di dunia. Penyakit ini menyebabkan angka kesakitan yang tinggi pada jutaan penduduk dunia setiap tahunnya.
Nur Wahyuniati, M.Imun M.Imun
doaj   +1 more source

Study of T1 Tobacco Transplastomic Plants Containing Human Gamma Interferon Gene (hIFNg) [PDF]

open access: yesمجله بیوتکنولوژی کشاورزی, 2014
In the recent decades the progress in plant biotechnology, especially in the field of molecular farming, has made it possible to produce a wide range of recombinant protein using plants as a novel production system and bioreactor.
Mozhgan Soleimani Zadeh   +3 more
doaj   +1 more source

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