Results 11 to 20 of about 1,329,149 (334)
The Interferon-Gamma Paradox in Cancer [PDF]
Journal of Interferon & Cytokine Research, 2019 Interferon-gamma (IFNG) has long been implicated as a central orchestrator of antitumor immune responses in the elimination stage of the immunoediting paradigm.
Zaidi Mr
semanticscholar +3 more sources
International Journal of Mycobacteriology, 2021 Mycobacterium tuberculosis (Mtb) and nontuberculous mycobacteria (NTM) remain the leading causes of lung disease and mortality worldwide. Interferon-gamma (IFN-γ) and its receptor (IFN-γR) play a key role in mediating immunity against Mtb and NTM.
Jalaledin Ghanavi +3 more
doaj +3 more sources
Mustansiriya Medical Journal, 2022 Background: Acromegaly is a rare endocrine disease, its incidence is 4-6 per million per years while its prevalence is 40-60 per million. The distinctive facial characteristics are prognathism prominent forehead, and large hands and feet.
Sabreen Hamodi Hamza +2 more
openaire +1 more source
Interferon-γ acutely augments inhibition of neocortical layer 5 pyramidal neurons [PDF]
, 2020 BACKGROUND: Interferon-γ (IFN-γ, a type II IFN) is present in the central nervous system (CNS) under various conditions. Evidence is emerging that, in addition to its immunological role, IFN-γ modulates neuronal morphology, function, and development in ...
Bräuer, Anja U. +7 more
core +1 more source
Interferon-Gamma at the Crossroads of Tumor Immune Surveillance or Evasion
Frontiers in Immunology, 2018 Interferon-gamma (IFN-γ) is a pleiotropic molecule with associated antiproliferative, pro-apoptotic and antitumor mechanisms. This effector cytokine, often considered as a major effector of immunity, has been used in the treatment of several diseases ...
F. Castro +4 more
semanticscholar +1 more source
UMYU Journal of Microbiology Research, 2020 Typhoid fever remains a significant public health challenge in developing countries, including Nigeria. The Widal test, widely used for diagnosing typhoid fever due to its simplicity and quick turnaround time, has raised concerns regarding its ...
Mujahid, N. S. +6 more
doaj +1 more source
Cytokines of Birds: Conserved Functions [PDF]
, 2001 Targeted disruptions of the mouse genes for cytokines, cytokine receptors, or components of cytokine signaling cascades convincingly revealed the important roles of these molecules in immunologic processes. Cytokines are used at present as drugs to fight
Göbel, Thomas W. F. +4 more
core +1 more source
Immunobiology, 1989 Article de synthese sur l'interferon gamma: role physiologique et utilisation therapeutique ...
Ijzermans, Jan N.M., Marquet, Richard L.
openaire +3 more sources
Open‐Label Pilot Study of Interferon Gamma–1b in Patients With Non‐Infantile Osteopetrosis
JBMR Plus, 2022 The only treatment currently available for patients with severe infantile osteopetrosis is hematopoietic cell transplantation (HCT). HCT‐related toxicity and mortality risks typically preclude its use in non‐infantile patients, and other therapies are ...
Andrew Nguyen +8 more
doaj +1 more source
Interferon-γ Inhibits Ebola Virus Infection.
PLoS Pathogens, 2015 Ebola virus outbreaks, such as the 2014 Makona epidemic in West Africa, are episodic and deadly. Filovirus antivirals are currently not clinically available.
Bethany A Rhein +11 more
doaj +1 more source