Results 1 to 10 of about 1,206,341 (327)

Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon gamma and bacterial lipopolysaccharide

Journal of Experimental Medicine, 1993
Inducible nitric oxide synthase (iNOS) can be expressed by many types of mammalian cells in response to diverse signals acting synergistically, including cytokines and microbial products.
Q. Xie, R. Whisnant, C. Nathan
semanticscholar   +1 more source

Reduced NK cell IFN-γ secretion and psychological stress are independently associated with herpes zoster. [PDF]

PLoS ONE, 2018
The pathogenesis of herpes zoster is closely linked to reduced varicella-zoster virus-specific cell-mediated immunity. However, little is known about the interplay between natural killer cells and psychological stress in the pathogenesis of herpes zoster.
Choon Kwan Kim, Youn Mi Choi, Eunsin Bae, Mihn Sook Jue, Hyung Seok So, Eung-Soo Hwang   +5 more
doaj   +1 more source

Interferon-Gamma: Treatment Horizons

Антибиотики и Химиотерапия, 2020
The review provides modern literature data on the system of interferons, their cells producers and target cells. Particular attention is paid to the immunomodulating effect of interferon-γ.
A. A. Khryanin, O. V. Reshetnikov
doaj  

Cerebral malaria: gamma-interferon redux

Frontiers in Cellular and Infection Microbiology, 2014
There are two theories that seek to explain the pathogenesis of cerebral malaria, the mechanical obstruction hypothesis and the immunopathology hypothesis.
Nicholas H Hunt, Helen J Ball, Anna S Hansen, Anna S Hansen, Loke Tim Khaw, Loke Tim Khaw, Jintao eGuo, Supun eBakmiwewa, Andrew J Mitchell, Valéry eCombes, Georges E.R. Grau   +10 more
doaj   +1 more source

Induction of interferon gamma production by natural killer cell stimulatory factor: characterization of the responder cells and synergy with other inducers

Journal of Experimental Medicine, 1991
We previously reported that natural killer cell stimulatory factor (NKSF), a heterodimeric lymphokine purified from the conditioned medium of human B lymphoblastoid cell lines, induces interferon gamma (IFN- gamma) production from resting peripheral ...
Susan, Chấn, Bice, Perussia, Jean, Gupta, Michiko., Kobayashi, Miloslav, Pospigil, Howard, Young, Stanley, Wolf, Deborah Young, Steven, Clark, G. Trinchieri   +17 more
semanticscholar   +1 more source

Some biological properties of the human amniotic membrane interferon

Memorias do Instituto Oswaldo Cruz, 1992
Human amniotic interferon was investigated to define the species specificity of its antiviral action and compare its anti-cellular and NK cell stimulating activities with those of other human interferons.
P. C. P. Ferreira, L. de la Roque, V. M. Rumjanek, R. R. Golgher   +3 more
doaj   +1 more source

Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets

Journal of Experimental Medicine, 1989
We purified poly(A)+ mRNA from the spleen and lymph nodes at designated times after infection with Leishmania major in genetically susceptible BALB/c and resistant C57BL/6 mice.
F. Heinzel, M. Sadick, Bettie J. Holaday, Robert L. Coffmanj, R. Locksley   +4 more
semanticscholar   +1 more source

Immune response-associated production of neopterin. Release from macrophages primarily under control of interferon-gamma

Journal of Experimental Medicine, 1984
Neopterin, a compound derived from GTP, represents a precursor molecule of biopterin that is an essential cofactor in neurotransmitter synthesis. We have recently reported that in vivo as well as in vitro immune responses are accompanied by an increased ...
C. Huber, J. R. Batchelor, D. Fuchs, A. Hausen, A. Lang, D. Niederwieser, G. Reibnegger, P. Swetly, J. Troppmair, H. Wachter   +9 more
semanticscholar   +1 more source

Interferon-gamma rescues dendritic cell calcineurin-dependent responses to Aspergillus fumigatus via Stat3 to Stat1 switching

iScience
Summary: Invasive pulmonary aspergillosis is a lethal opportunistic fungal infection in transplant recipients receiving calcineurin inhibitors. We previously identified a role for the calcineurin pathway in innate immune responses to A.
Amit Adlakha, Thomas J. Williams, Xinxin Shou, Anna K. Reed, Boris Lenhard, Darius Armstrong-James   +5 more
doaj   +1 more source

First report of hepatobiliary Mycobacterium avium infection developing obstructive jaundice in a patient with neutralizing anti–interferon-gamma autoantibodies

New Microbes and New Infections, 2019
This study describes a patient who experienced hepatobiliary Mycobacterium avium infection associated with neutralizing anti–interferon gamma (IFN-γ) autoantibodies during treatment for disseminated M. avium disease. Hepatobiliary M.
H. Namkoong, T. Asakura, M. Ishii, S. Yoda, K. Masaki, T. Sakagami, E. Iwasaki, Y. Yamagishi, T. Kanai, T. Betsuyaku, N. Hasegawa   +10 more
doaj   +1 more source