Results 11 to 20 of about 1,206,341 (327)
Interferon Gamma in Leishmaniasis [PDF]
Frontiers in Immunology, 2013 Leishmaniasis is a complex disease that is caused by parasites of the Leishmania genus. Leishmania are further classified into several complexes, each of which can engage in distinct interactions with mammalian hosts resulting in differing disease ...
Peter Kima, Lynn Soong, Soong Lynn
exaly +6 more sources
Interferon-Gamma-Mediated Osteoimmunology [PDF]
Frontiers in Immunology, 2018 Osteoimmunology is the interdiscipline that focuses on the relationship between the skeletal and immune systems. They are interconnected by shared signal pathways and cytokines.
Xijie Yu, Li Tian, Yu Xijie
exaly +6 more sources
The Interferon-Gamma Paradox in Cancer [PDF]
Journal of Interferon and Cytokine Research, 2019 Interferon-gamma (IFNG) has long been implicated as a central orchestrator of antitumor immune responses in the elimination stage of the immunoediting paradigm.
M Raza Zaidi
exaly +4 more sources
International Journal of Mycobacteriology, 2021 Mycobacterium tuberculosis (Mtb) and nontuberculous mycobacteria (NTM) remain the leading causes of lung disease and mortality worldwide. Interferon-gamma (IFN-γ) and its receptor (IFN-γR) play a key role in mediating immunity against Mtb and NTM.
Jalaledin Ghanavi +3 more
doaj +4 more sources
Interferon-Gamma at the Crossroads of Tumor Immune Surveillance or Evasion
Frontiers in Immunology, 2018 Interferon-gamma (IFN-γ) is a pleiotropic molecule with associated antiproliferative, pro-apoptotic and antitumor mechanisms. This effector cytokine, often considered as a major effector of immunity, has been used in the treatment of several diseases ...
Karine Serre +2 more
exaly +2 more sources
Interferon gamma in cancer immunotherapy
Cancer Medicine, 2018 Immune system can recognize self vs transformed self. That is why cancer immunotherapy achieves notable benefits in a wide variety of cancers. Recently, several papers reported that immune checkpoint blockade therapy led to upregulation of IFNγ and in ...
Ling Ni, Jian Lu
doaj +2 more sources
Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression
Cell Reports, 2017 PD-L1 and PD-L2 are ligands for the PD-1 immune inhibiting checkpoint that can be induced in tumors by interferon exposure, leading to immune evasion. This process is important for immunotherapy based on PD-1 blockade.
Angel Garcia-Diaz +18 more
doaj +2 more sources
Pulmonary Medicine, 2013 A profusion of articles have been published on the accuracy and uses of interferon-gamma releasing assays. Here we review the clinical applications, advantages, and limitations of the tuberculin skin test and interferon-gamma release assays and provide ...
A. Trajman, R. E. Steffen, D. Menzies
doaj +2 more sources
Immune hyperactivity in hemodialysis patients is associated with interferon gamma-induced trained immunity. [PDF]
iScienceJonkman I +12 more
europepmc +2 more sources
Dapagliflozin confers protection against ferroptosis in cardiomyocyte via the inhibition of interferon-gamma pathway. [PDF]
Mol Biol RepMenaldi RR +7 more
europepmc +3 more sources