Results 31 to 40 of about 278,920 (292)

Evaluation of Interferon-gamma Application for Recognition of Patients Afflicted by Non-healing Cutaneous Leishmaniasis [PDF]

open access: yesBiological Journal of Microorganism, 2017
Introduction:Different studies undertaken in the animal modeling show that Interferon-gamma deficiency impairs healing process of Leishmania infection.
Mohammad Moafi   +10 more
doaj  

The preventive effects of natural adjuvants, G2 and G2F on tracheal responsiveness and serum IL-4 and IFN-γ (th1/th2 balance) in sensitized guinea pigs

open access: yesClinics, 2014
OBJECTIVE:The effects of natural adjuvants on lung inflammation and tracheal responsiveness were examined in sensitized guinea pigs.METHODS:The responses of guinea pig tracheal chains and the serum levels of interleukin-4 and interferon-gamma were ...
Mohammad Hossein Boskabady   +5 more
doaj   +1 more source

IFN-γ and IL-10: seric and placental profile during pig gestation Seric and placental cytokines in pig gestation

open access: yesAnais da Academia Brasileira de Ciências, 2023
Concentration of interferon-gamma and interleukin-10 in maternal serum and in maternal and fetal porcine placental extracts from different gestation periods was determined.
CAROLINA VÉLEZ   +4 more
doaj   +1 more source

Performance of commerical blood tests for the diagnosis of latent tuberculosis infection in children and adolescents [PDF]

open access: yes, 2009
BACKGROUND: The accurate diagnosis of latent tuberculosis infection reduces the risk of progression to severe disseminated disease. However, in young children, a major limitation of the standard tuberculin skin test is that false-negative results cannot ...
B. Meccugni   +10 more
core   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta   +6 more
wiley   +1 more source

Use of interferon gamma release assay to assess latent tuberculosis infection among healthcare workers in Hong Kong [PDF]

open access: yes, 2015
Key Messages 1. Overall baseline interferon gamma release assay positivity was 20.7%. 2. The conversion to interferon gamma release assay positivity at 3 months was 8.85% in the exposed group and 4.54% in the non-exposed group using the conventional ...
Chan, JWM   +9 more
core  

Az Interferon-gamma által indukált jelátvitel mechanizmusa humán újszülöttek mononukleáris fagocitasejtjeiben = Interferon-gamma induced signaling in mononuclear phagocytes from human neonates [PDF]

open access: yes, 2006
Humán újszülöttek és felnőttek mononukleáris (MN) fagocitasejtjeiben a foszforilált STAT-1 kimutatásához olyan monoclonalis antitesteket használtunk, amelyek specifikusan kötődnek a foszforilált STAT-1 molekulákhoz, de nem kötődnek a natív STAT-1 ...
Erdős, Melinda   +4 more
core  

Is Adenosine Deaminase in Pleural Fluid a Useful Marker for Differentiating Tuberculosis from Lung Cancer or Mesothelioma in Japan, a Country with Intermediate Incidence of Tuberculosis? [PDF]

open access: yes, 2011
The objective of this study was to evaluate the utility of the determination of adenosine deaminase (ADA) level in pleural fluid for the differential diagnosis between tuberculous pleural effusion (TPE) and malignant pleural effusion (MPE) in Japan, a ...
Aoe, Keisuke   +9 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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