Results 211 to 220 of about 35,670 (265)

Dnmt3a Mutations Limit Normal and Autoreactive CD4+ T Follicular Helper Responses and Attenuate T Cell–Driven Joint Inflammation

Arthritis &Rheumatology, EarlyView.
Objective Somatic DNMT3A mutations are the most common drivers of clonal hematopoiesis in patients with rheumatoid arthritis (RA) and have been associated with seropositive disease and increased markers of inflammation. These mutations are predominantly hypomorphic or dominant‐negative, reducing DNMT3A function.
Yunbing Shen, Sanjaykumar Boddul, Zhaojun Li, Zsolt Kasza, Marlene Schülein, Bruno Raposo, Karine Chemin, Per‐Johan Jakobsson, Alexander Espinosa, Lars Klareskog, Fredrik Wermeling   +10 more
wiley   +1 more source

The underdiagnosis of pulmonary tuberculosis in non-TB-designated health facilities in China: a nationwide retrospective study. [PDF]

BMC Infect Dis
Li X, Ou X, Liu X, Li Y, Xing R, Xu C, Zhao Y, Du X, Li T.   +8 more
europepmc   +1 more source

Peripheral Blood DNA Methylation Changes Precede Lymphoma Diagnosis in Primary Sjögren's Disease

Arthritis &Rheumatology, EarlyView.
Objective Primary Sjögren's disease (SjD) is a systemic autoimmune disease associated with an increased risk of lymphoma. The molecular mechanisms underlying lymphomagenesis remain poorly understood, and sensitive biomarkers for early identification of patients at high risk of developing lymphoma are lacking.
Hanna Lidberg, Cecilia Fugmann, Juliana Imgenberg‐Kreuz   +2 more
wiley   +1 more source

Multiparameter antigen-specific immunoprofiling in subjects with negative IGRA and TST results with potential <i>M. tuberculosis</i> exposures. [PDF]

Front Cell Infect Microbiol
Pathakumari B, Gutierrez LE, Faisal SA, Sanchez PA, Daniel K, Van Keulen VP, Hilgart HR, Reddy MR, Theel E, Laniado-Laborin R, Clain JM, Peikert T, Bailey RC, Escalante P.   +13 more
europepmc   +1 more source

Safety, tolerability, and concordance with interferon-γ release assays of a recombinant ESAT6-MPT64 skin test: a phase 1 randomized clinical trial. [PDF]

Front Immunol
Ou X, Liu G, Peng B, Li Y, Yan H, Chu N, Zhao B, Zhao Y, Du J.   +8 more
europepmc   +1 more source

Latent tuberculosis screening for inflammatory bowel disease in tuberculosis endemic region remains porous and suboptimal: A multicentre study. [PDF]

World J Gastroenterol
Jha DK, Prasad S, Valsan A, Mishra S, Nair P, Koshy AK, Singh S, Prasad AS, Shukla R, Ahamed R, Augustine P, Natarajan K, Peddi K, Kulkarni A, Bhatia S, Pachisia AV, Singh PK, Jena A, Gupta S, Jain S, Padmaprakash K, Kakadiya R, Kumar A, Shukla S, Dutta U, Hande V, Thareja S, Sharma V.   +27 more
europepmc   +1 more source

Cause of chronic diarrhoea. [PDF]

Gut
Cao T, Wang H.
europepmc   +1 more source

Relapsing polychondritis presenting with intractable chronic cough, acute visual disturbance, and hearing loss. [PDF]

Korean J Intern Med
Kim H, Kong E.
europepmc   +1 more source

Interferon-Gamma Release Assays Versus Tuberculin Skin Test for Active Tuberculosis Diagnosis: A Systematic Review and Diagnostic Meta-Analysis. [PDF]

Diagnostics (Basel)
Tobaiqi MA, Alshamrani MN, Sriram S, Mahmoud AB, Fadlalmola HA, Albadrani M.   +5 more
europepmc   +1 more source