Results 251 to 260 of about 58,702 (314)

Relapsing polychondritis presenting with intractable chronic cough, acute visual disturbance, and hearing loss. [PDF]

Korean J Intern Med
Kim H, Kong E.
europepmc   +1 more source

Intravenous Lipopolysaccharide Challenge in Healthy Participants Reveals Pharmacodynamic Markers in Blood and Bone Marrow for Early‐Phase Oncology Drug Development

Clinical Pharmacology &Therapeutics, EarlyView.
Demonstrating pharmacological effects in early‐phase oncology clinical trials remains challenging, largely due to the lack of robust pharmacodynamic markers. Lipopolysaccharide (LPS) is used as an immune challenge agent in healthy participants to study drugs for autoimmune conditions.
Igor Radanović, Ingrid Tomljanović, Wieke H. Grievink, Diana R. Pereira, Michelle Osse, Peter van Balen, Maria J. Juachon, Marieke L. de Kam, Lisa Pagan, Manon A.A. Jansen, Matthijs Moerland, Jacobus J. Bosch   +11 more
wiley   +1 more source

Tuberculosis infection in an urban homeless population. [PDF]

Epidemiol Infect
Moynan D, Donohue S, Fitzgerald A, Alemayehu H, Groarke E, Mooney A, Gaffney F, Brandon KA, Jones K, Conlon N, Ni Cheallaigh C, Allen N.   +11 more
europepmc   +1 more source

Population Genomics Insights into Pharmacogenomic Differentiation Between East Asians and Europeans

Clinical Pharmacology &Therapeutics, EarlyView.
Genetic variation contributes substantially to interindividual and interpopulation differences in drug response, yet most pharmacogenomic studies remain biased toward European populations. Here, we systematically assessed pharmacogenomic variation across East Asians (EAS) and Europeans (EUR) using public genomic datasets and investigated the potential ...
Sihan Chen, Hongpu Chen, Shuhua Xu
wiley   +1 more source

Cost-effectiveness analysis of tuberculosis screening in diabetic patients in China: a decision-analytic Markov model. [PDF]

Front Public Health
Song HW, Lin Y, Wan TE, Zhang CF, Pan JS.   +4 more
europepmc   +1 more source

Prevalence of latent tuberculosis infection in Malaysia: the first systematic review and meta-analysis. [PDF]

BMC Infect Dis
Wada Y, Afolabi HA, Irekeola AA, Bello KE, Yean CY, Rahman ZA.   +5 more
europepmc   +1 more source

Interferon-Gamma Release Assays Versus Tuberculin Skin Test for Active Tuberculosis Diagnosis: A Systematic Review and Diagnostic Meta-Analysis. [PDF]

Diagnostics (Basel)
Tobaiqi MA, Alshamrani MN, Sriram S, Mahmoud AB, Fadlalmola HA, Albadrani M.   +5 more
europepmc   +1 more source

α-Linolenic acid-driven nano-liposomes from purslane seed oil modulate p-JAK2/p-STAT3 to combat acute liver failure. [PDF]

Biosci Rep
Ali SO, Hegazy D, Kamel IS, Shalan NH, ElMonier AA.   +4 more
europepmc   +1 more source

<i>ACSL4</i>-driven ferroptosis susceptibility as a targetable vulnerability in monocytic acute myeloid leukemia. [PDF]

Front Oncol
De Marchi F, Gottardi M.
europepmc   +1 more source