Results 131 to 140 of about 779,562 (365)
INHIBITION OF PROTEIN SYNTHESIS IN NONINFECTED L CELLS BY PARTIALLY PURIFIED INTERFERON PREPARATIONS [PDF]
, 1968 Terry C. Johnson +2 more
openalex +1 more source
H2O2‐Generating Advanced Nanomaterials for Cancer Treatment
Advanced Functional Materials, EarlyView.H2O2‐generating nanoplatforms can exploit tumor redox imbalance for O2 and toxic reactive oxygen species generation, leading to hypoxia reversal, and apoptosis of cancer cells, respectively. This review highlights the mechanisms of these nanoplatforms, including exogenous H₂O₂ delivery, endogenous amplification, and metal peroxides, which leads to ...
Kiyan Musaie +8 more
wiley +1 more source
Journal of Infectious Diseases, 2015 Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe disease in human with an overall case-fatality rate of >35%. Effective antivirals are crucial for improving the clinical outcome of MERS.
J. Chan +15 more
semanticscholar +1 more source
Demonstration, Mass Production and Characterization of a Heavy Molecular Weight Human Interferon [PDF]
, 1967 Françoise Fournier +2 more
openalex +1 more source
Advanced Functional Materials, EarlyView.A visible light‐responsive polyacrylamide‐azobenzene hydrogel enables safe, reversible stiffness control for studying cell mechanobiology without harmful UV exposure. This approach reveals stem cells respond rapidly to mechanical changes, showing altered shape and protein distribution within one hour.
Aafreen Ansari +11 more
wiley +1 more source
Fatigue in Sjögren's Syndrome: A Search for Biomarkers and Treatment Targets
Frontiers in Immunology, 2019 Background: Primary Sjögren's syndrome (pSS) is a systemic autoimmune disease, where patients often suffer from fatigue. Biological pathways underlying fatigue are unknown.
Iris L. A. Bodewes +10 more
doaj +1 more source
Mathematical analysis of a mouse experiment suggests little role for resource depletion in controlling influenza infection within host [PDF]
arXiv, 2017 How important is resource depletion (e.g. depletion of target cells) in controlling infection within a host? And how can we distinguish between resource depletion and other mechanisms that may contribute to decline of pathogen load or lead to pathogen clearance? In this paper we examine data from a previously published experiment.
arxiv
Advanced Functional Materials, EarlyView.A hydrogel for intra‐articular injection for the treatment of rheumatoid arthritis (RA) is formulated and comprehensively studied. After administration, the hydrogel induces a metabolic reprogramming of immunometabolism of macrophages to trigger fatty acid oxidation subsequently inducing polarization of anti‐inflammatory M2 macrophages. This results in
Yutong Song +8 more
wiley +1 more source
The Long Non-coding RNA NRIR Drives IFN-Response in Monocytes: Implication for Systemic Sclerosis
Frontiers in Immunology, 2019 TLR4 activation initiates a signaling cascade leading to the production of type I IFNs and of the downstream IFN-stimulated genes (ISGs). Recently, a number of IFN-induced long non-coding RNAs (lncRNAs) that feed-back regulate the IFN response have been ...
Barbara Mariotti +15 more
doaj +1 more source
Renal function changes in chronic hepatitis B patients [PDF]
arXivThe best way to treat chronic hepatitis B is with pegylated interferon alone or with oral antiviral drugs. There is limited research comparing the renal safety of entecavir and tenofovir when used with pegylated interferon. This study will compare changes in renal function in chronic hepatitis B patients treated with pegylated interferon and either ...
arxiv