Results 201 to 210 of about 582,181 (313)

Biomarker-stratified efficacy and safety of biologics in systemic lupus erythematosus: a systematic review and meta-analysis. [PDF]

Lupus Sci Med
Alqatari SG, Alkuwaiti MA, Al-Harbi FA, Alabdullah MM, Zeidan AA, AlYousef NH, Alsaad MA, Abualjamal RY, Alkuwaiti FA, Al-Abdulwahab AA, AlZuhair HM, AlNujaidi DY, Alasaker NA, Hasan MA, Azzam AY.   +14 more
europepmc   +1 more source

Caspase‐3/GSDME‐Mediated Trophoblast Pyroptosis and Reciprocal Macrophage Polarization Contribute to Inflammation in Early‐Onset Preeclampsia

Advanced Science, EarlyView.
In trophoblast cells, T/S (TNFα + SM164) activated caspase‐3, which cleaved GSDME to switch apoptosis to pyroptosis, causing cell swelling, membrane rupture, and release of LDH, HMGB1, IL‐1β and IL‐18. These cytokines induced pro‐inflammatory macrophage polarization, which in turn reinforced pyroptotic signaling in trophoblasts, amplifying systemic ...
Baoying Huang, Weinan Deng, Shilei Bi, Yifan Wang, Zhaowei Tu, Lijun Huang, Lili Du, Lizi Zhang, Zhoushan Feng, Wei Sun, Tengfei Liu, Julia Kzhyshkowska, Haibin Wang, Jingsi Chen, Dunjin Chen, Shuang Zhang   +15 more
wiley   +1 more source

Regulatory dynamics of IFI44L in systemic lupus erythematosus: the interplay of type I interferon and c-Jun. [PDF]

Lupus Sci Med
Wang Y, Yang M, Ma H, Ma X, Huo Z, Ma Z, Dang J.   +6 more
europepmc   +1 more source

Spatially Resolved Multiomics Reveals Metabolic Remodeling and Autophagy Activation in Adamantinomatous Craniopharyngiomas

Advanced Science, EarlyView.
Multiomics integration analysis reveals the “cystic fluid–tumor cell” metabolic coupling that mediates active choline/ethanolamine uptake of tumor cells from cystic fluid and PC/PE synthesis pathways reprogramming that mediating autophagy pathway activation within ACP. ABSTRACT Adamantinomatous craniopharyngioma (ACP), a benign yet highly recurrent and
Dongting Chen, Yahui Gao, Yulin Wang, Ting Lei, Zheng Qu, Yuhan An, Jiaxu Fu, Xin Li, Fangjun Liu, Yan Li   +9 more
wiley   +1 more source

Correction: TRIM21 regulation of IRF-mediated type I interferon signaling in systemic autoimmune diseases. [PDF]

Front Immunol
Panlu K, Wang Y, Zhu X, Lin Z, Fang T, Yao X, Xie Z, Wang X.   +7 more
europepmc   +1 more source

Review of Interferon Psalms by Luke Davies

, 2012
Tina Giannoukos
openalex   +1 more source

NAP1 switches from an activator to a limiter of interferon induction by trapping TBK1 in condensates [PDF]

Damien Glon, Quentin Riller, Frédéric Rivière, Benjamin Léonardon, Ariane Guillemot, Laïla Sago, Olivier Pellé, Duong Ho‐Nhat, Karine Brochard, Brigitte Bader‐Meunier, Marie‐Louise Frémond, Alice Lepelley, Yanick J. Crow, Maud Tusseau, Alexandre Bélot, Cécile Lagaudrière‐Gesbert, Frédéric Rieux‐Laucat, Yves Gaudin   +17 more
openalex   +1 more source

Cytoprotection Concepts for Ischemic Stroke in the Recanalization Era

Advanced Science, EarlyView.
This review provides detailed information on modern cytoprotective strategies for ischemic stroke in the context of recanalization therapies. It derives their rationale based on contemporary knowledge of stroke pathophysiology and discusses the role of advanced imaging approaches as well as concepts for novel clinical trial designs.
Johannes Boltze, Marc Fisher
wiley   +1 more source

Interferon-γ Level in Patients with Atopic Dermatitis

, 2019
Ahmed Saeed Abdul-Jabbar, Samet E. Kasem
openalex   +1 more source

Figure S2 from Subsets of interferon signaling predict response to immune checkpoint blockade in melanoma patients

Brooke Horowitch, Daniel Y. Lee, Min Ding, Sandra Martínez-Morilla, Thazin Nwe Aung, Feriel Ouerghi, Xueting Wang, Wei Wei, William Damsky, Mario Sznol, Harriet M. Kluger, David L. Rimm, Jeffrey J. Ishizuka   +12 more
openalex   +1 more source