Results 211 to 220 of about 1,191,146 (396)

Microphysiological Systems in Cancer Research: Advancing Immunotherapy through Tumor Microenvironment‐Integrated Organ‐On‐Chip Models

Advanced Therapeutics, EarlyView.
Emerging microphysiological systems reproduce the spatial, biochemical, and cellular complexity of the tumor microenvironment, surpassing 2D cultures and murine models. By integrating patient‐derived tumors, perfusable vasculature, and immune trafficking, these organ‐on‐chip platforms reveal mechanisms of immune evasion, predict therapeutic responses ...
Fabiana Moresi, Francesco Noto, Jyothsna Vasudevan, Xavier Bisteau, Giulia Adriani, Andrea Pavesi   +5 more
wiley   +1 more source

Global trends and insights in interferon therapy for chronic hepatitis B: a bibliometric analysis. [PDF]

Virol J
Duan L, Liu Y, Wu D, Wen T, Huang S, Zhu X, Sun G, Yang G, Hu Y, Pu S, Zeng Q, Yang Q.   +11 more
europepmc   +1 more source

Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression

Cell Reports, 2017
A. García-Díaz, D. Shin, B. H. Moreno, Justin D. Saco, Helena Escuin-Ordinas, G. A. Rodriguez, J. Zaretsky, Lu Sun, Willy Hugo, Xiaoyan Wang, Giulia Parisi, Cristina Puig Saus, D. Torrejon, T. Graeber, Begonya Comin-Anduix, S. Hu-Lieskovan, R. Damoiseaux, R. Lo, A. Ribas   +18 more
semanticscholar   +1 more source

Cytokine Engineering Approaches for Regenerative Medicine

Advanced Therapeutics, EarlyView.
Engineered cytokines represent a powerful strategy to promote tissue repair and regeneration by precisely modulating immune responses. This review highlights recent advances in cytokine engineering, including strategies to enhance half‐life, improve tissue and cell targeting, and control receptor signaling.
Shiyi Li, Wenhao You, Mikaël M. Martino
wiley   +1 more source

Rubella Virus: Role of Interferon during Infection of African Green Monkey Kidney Tissue Cultures [PDF]

, 1967
Ken T. Wong, Samuel Baron, Thomas G. Ward   +2 more
openalex   +1 more source

Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy

Advanced Therapeutics, EarlyView.
This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar, Weiwei Guo, Xin Shen, Yimeng Fang, Yilin Liu, Peng‐Yuan Wang, Roey Elnathan, Yaping Chen   +7 more
wiley   +1 more source

A fresh look at immunocytometry's role in personalized rheumatology. [PDF]

Rheumatology (Oxford)
Valencic E, Tommasini A, Taddio A.
europepmc   +1 more source

Enhancing the Effectiveness of Chemotherapy in Osteosarcoma by Targeting Tumour‐Associated Macrophages (TAMs) through STING Activation

Advanced Therapeutics, EarlyView.
Osteosarcoma isa highly aggressive bone cancer with an immunosuppressive tumor microenvironment that limits immunotherapy. This study explores STING pathway activation to reprogram tumor‐associated macrophages into a tumoricidal M1‐like phenotype and enhance doxorubicin efficacy. Results show that doxorubicin alone failed to activate the STING pathway,
Jordan C. O'Donoghue, Amanda Guitián‐Caamaño, Maeve Boyce, Fiona E. Freeman   +3 more
wiley   +1 more source

Opening and closing of a cryptic pocket in VP35 toggles it between two different RNA-binding modes. [PDF]

Elife
Mallimadugula UL, Cruz MA, Vithani N, Zimmerman MI, Bowman GR.   +4 more
europepmc   +1 more source

Interferon target-gene expression and epigenomic signatures in health and disease

Nature Immunology, 2019
F. Barrat, M. Crow, L. Ivashkiv
semanticscholar   +1 more source