Results 231 to 240 of about 1,191,146 (396)

Oral fingolimod or intramuscular interferon for relapsing multiple sclerosis.

New England Journal of Medicine, 2010
Jeffrey A. Cohen, F. Barkhof, G. Comi, H. Hartung, B. Khatri, X. Montalban, J. Pelletier, R. Capra, P. Gallo, G. Izquierdo, K. Tiel‐Wilck, A. de Vera, James Jin, T. Stites, Stacy Wu, S. Aradhye, L. Kappos   +16 more
semanticscholar   +1 more source

Hypoglycemia Induces Diabetic Macrovascular Endothelial Dysfunction via Endothelial Cell PANoptosis, Macrophage Polarization, and VSMC Fibrosis

Advanced Science, EarlyView.
This study investigates hypoglycemia‐induced diabetic macrovascular endothelial dysfunction. It reveals that hypoglycemia triggers ZBP1‐dependent PANoptosis of endothelial cells, proinflammatory polarization of macrophages, and fibrosis of vascular smooth muscle cells (VSMCs) in diabetic mice.
Deyu Zuo, Yuce Peng, Guozhi Zhao, Zhesheng Cheng, Minghao Luo, Dingyi Lv, Shuting Chang, Na Li, Yanyao Huang, Xunjia Li, An He   +10 more
wiley   +1 more source

Case Report: Heterozygous <i>ADAR</i> c.3019G>A pathogenic variant associated with variable neurological symptoms and incomplete penetrance in a four-generational family. [PDF]

Front Immunol
Bauer AK, Marquardt I, Sundermann B, Wolf C, Raupach K, Grundmann-Hauser K, Gieldon L, Otterbach M, Maurer M, Haack T, Lee-Kirsch MA, Korenke GC, Hitz MP.   +12 more
europepmc   +1 more source

METAMORPHOSIS OF HUMAN AMNION CELLS INDUCED BY PREPARATIONS OF INTERFERON

, 1961
Ion Gresser
openalex   +1 more source

Role of Interferon in the Propagation of MM Virus in L Cells [PDF]

, 1969
David Giron
openalex   +1 more source

MCT1‐mediated Lactate Shuttle to Mitochondria Governs Macrophage Polarization and Modulates Glucose Homeostasis by Affecting β Cells

Advanced Science, EarlyView.
This study demonstrates that the transport of lactate to the mitochondria is of critical importance in determining the functions of macrophages by altering mitochondrial respiration. In macrophages, this lactate transport mechanism regulates glucose homeostasis by influencing the functions of insulin‐secreting cells in the pancreatic islets.
Lingling Chen, Yijun Lin, Xinyu Zhu, Shixuan Zhuo, Zixuan Li, Cheng Guo, Xiaoyi Ye, Jinzhu Chen, Shuying Wang, Yan Chen   +9 more
wiley   +1 more source

Transforming growth factor beta (TGF-β) induces type 1 interferon signalling in systemic sclerosis keratinocytes through the chloride intracellular channel 4 (CLIC4). [PDF]

Arthritis Res Ther
Wasson CW, Dibb SL, Caballero-Ruiz B, Bamigbola IE, Di Donato S, Madourie-Clavane EM, Wells R, Kakkar V, De Lorenzis E, Bryon J, Derrett-Smith E, Denton CP, El-Sherbiny Y, Meakin PJ, Ross RL, Del Galdo F.   +15 more
europepmc   +1 more source

Role of Interferon in Replication of Virulent and Attenuated Strains of Measles Virus

, 1969
H. Mirchamsy, Fred Rapp
openalex   +1 more source

Disruption of ARID1B Recruitment to the Nuclear Pore Complex as a New Anticancer Therapeutic Strategy

Advanced Science, EarlyView.
This study identifies ARID1B as a chromatin‐bound driver of tumor growth in TNBC. ARID1B impairs ARID1A function and directly activates oncogenic programs through SWI/SNF remodeling. Its nuclear localization, mediated by the KPNA2–KPNB1–RANBP2 import machinery, is essential for its tumor‐promoting activity.
Olena Odnokoz, Anupam Banerjee, Xin Cui, Lidan Zeng, Amad Uddin, Christopher Li, Yueming Zhu, Mengyuan Zhang, Xiaodong Lu, Nagendra S. Yarla, Lu Wang, Jindan Yu, Jonathan C. Zhao, Ivet Bahar, Yong Wan   +14 more
wiley   +1 more source

Optogenetic‐Controlled iPSC‐Based Vaccines for Prophylactic and Therapeutic Tumor Suppression in Mice

Advanced Science, EarlyView.
This study develops an a red/far‐red light‐controlled iPSC‐based vaccines (RIVA) based on the chimeric photosensory protein FnBphP and its interaction partner LDB3 for cancer immunotherapy. The RIVA preserves the multiple intrinsic tumor antigens of iPSCs and enables optogenetic control of the expression of the immune adjuvant type I interferon β under
Longliang Qiao, Lingxue Niu, Zhihao Wang, Di Dai, Shasha Tang, Xiaoding Ma, Zhenqiang Deng, Guiling Yu, Yang Zhou, Tao Yan, Xingwan Liu, Deqiang Kong, Linfeng Hu, Xiang Li, Junwei Zhao, Fengfeng Cai, Meiyan Wang, Haifeng Ye   +17 more
wiley   +1 more source